Hodgkin’s Disease: Internal Mammary Lymph Nodes Relapse Diagnosed by Gallium-67 Scintigraphy

Gloria Ruíz Herná; Y. Pallardó; J. Garcia Conde; D. Ramos; J. Ampudia; F. J. Castillo; C. Romero

doi:10.1055/s-0038-1632198

Nuklearmedizin - NuclearMedicine, Table of Contents

Nuklearmedizin 1999; 38(03): 90-94
DOI: 10.1055/s-0038-1632198

Originalarbeiten — Original Articles

Schattauer GmbH

Hodgkin’s Disease: Internal Mammary Lymph Nodes Relapse Diagnosed by Gallium-67 Scintigraphy

Morbus Hodgkin: Lymphknotenrezidiv im Bereich der Brust, durch Gallium-67 Szintigraphie diagnostiziert

Authors

Gloria Ruíz Herná

¹Servicio de Medicina Nuclear,
Y. Pallardó

²S. Radiologfa,
J. Garcia Conde

³S. Hematologfa y Oncologfa Médica,
D. Ramos

⁴S. Anatomfa Patolögica, Hospital Clfnico Universitario, València, Spain
J. Ampudia

¹Servicio de Medicina Nuclear,
F. J. Castillo

¹Servicio de Medicina Nuclear,
C. Romero

¹Servicio de Medicina Nuclear,

Abstract

Summary

This article presents the case of a 62-year-old man with treated Hodgkin’s disease who had internal mammary lymph nodes relapse after a complete initial response. These masses were gallium avid. These findings were explained by histologically documented Hodgkin’s relapse, the first such case reported in that localization without chest wall involvement. The literature on mediastinal Hodgkin’s disease and diagnostic procedures are reviewed.

Zusammenfassung

Beschrieben wird der Fall eines 62jährigen Mannes, der nach initial erfolgreicher Therapie eines Morbus Hodgkin ein Lymphknotenrezidiv im Bereich der Brust aufweist. Die Lymphknoten reicherten Gallium an. Histologisch wurde das Hodgkinrezidiv gesichert. Es handelt sich um den ersten in diesem Bereich beschriebenen Fall ohne Infiltration der Brustwand. Die Literatur über mediastinalen Morbus Hodgkin und diagnostisches Vorgehen wurde überprüft.

Key words

Hodgkin’s disease - internal mammary relapse - Ga-67 scintigraphy

Schüsselwörter

Morbus Hodgkin - Lymphknotenrezidiv im Bereich der Brust - Ga-67-Szintigraphie

Full Text

References

REFERENCES
1 Castellino RA, Blank N, Hoppe RT. et al. Hodgkin disease: Contributions of chest CT in the initial staging evaluation. Radiology 1986; 160: 603-5.
2 Meis JM, Butler JJ, Osborne BM. Hodgkin’s disease involving the breast and chest wall. Cancer 1986; 57: 1859-65.
3 Reverter JC, Vinolas N, Montserrat E, Rozman C. Hodgkin’s disease in external mammary lymph nodes. Ann Int med 1985; 103: 964.
4 Firth LA. Hodgkin’s disease presenting at the elbow. Lancet 1978; 2: 111.
5 Goldman JM. Parasternal chest wall involvement in Hodgkin’s disease. Chest 1971; 59: 133-7.
6 Diehl LF, Hopper KD, Giguere J, Granger E, Lesar M. The pattern of intrathoracic Hodgkin’s disease assed by Computed Tomography. J Clin Oncol 1991; 9: 438-43.
7 Front D, Shalom RB, Epelbaum R, Haim N, Ben-Arush MW, Ben-Shalar M. et al. Early detection of lymphoma recurrence with Gallium-67 scintigraphy. J Nucl Med 1993; 34: 2101-4.
8 Kostakoglu L, Yeh SDJ, Portlock C, Heelan R, Yao TJ, Niedzwiecki D. et al. Validation of Gallium-67 Citrate single photon emission computed tomography in biopsy-confirmed residual Hodgkin’s disease in the mediastinum. J Nucl Med 1992; 33: 345-50.
9 Salloum E, Brandt DS, Caride VJ, Cornelius E, Zelterman D, Schubert W. et al. Gallium scans in the management of patients with Hodgkin’s disease: a study of 101 patients. J Clin Oncol 1997; 15: 518-27.
10 Gasparini MD, Balzarini L, Castellani MR, Tess JDT, Maffioli LS, Petrillo R. et al. Current role of gallium scan and magnetic resonance imaging in the management of mediastinal Hodgkin lymphoma. Cancer 1993; 72: 577-82.
11 Höh CK, Glaspy J, Rosen P, Dalhbom M, Lee SJ, Kunkel L. et al. Whole-Body FDGPET imaging for staging of Hodgkin’s disease and lymphoma. J Nucl Med 1997; 38: 343-8.