Vet Comp Orthop Traumatol 2018; 31(03): 159-169
DOI: 10.1055/s-0038-1631878
Original Research
Schattauer GmbH Stuttgart

Clinical Efficacy of Bone Reconstruction Surgery with Frozen Cortical Bone Allografts for Nonunion of Radial and Ulnar Fractures in Toy Breed Dogs

Shuntaro Munakata
Division of Veterinary Surgery, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan
,
Yukari Nagahiro
Division of Veterinary Surgery, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan
,
Daichi Katori
Division of Veterinary Surgery, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan
,
Norihiro Muroi
Division of Veterinary Surgery, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan
,
Hiroyuki Akagi
Division of Veterinary Surgery, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan
,
Nobuo Kanno
Division of Veterinary Surgery, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan
,
Yasuji Harada
Division of Veterinary Surgery, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan
,
Shinya Yamaguchi
Division of Veterinary Surgery, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan
,
Kei Hayashi
Department of Clinical Sciences, Cornell University, College of Veterinary Medicine, Ithaca, New York, United States
,
Yasushi Hara
Division of Veterinary Surgery, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan
› Author Affiliations
Further Information

Publication History

08 March 2017

19 December 2017

Publication Date:
23 April 2018 (eFirst)

Abstract

Objective To evaluate the effectiveness of frozen cortical bone allografts (FCBA) in the treatment of severe radial and ulnar atrophic nonunion fractures.

Animals Toy breed dogs with nonunion of radial and ulnar fractures (n = 15).

Methods Severe atrophic nonunion fractures were treated with FCBA (eight infected and seven non-infected fractures). Radiographs obtained immediately after surgery, and 1, 2, 3, 6 and 12 months later were evaluated and scored for the periosteal reaction at the bone regeneration sites, the healing process in the bone connection areas at both the proximal and distal sites, and the bone remodelling process within the allografts.

Results Improvements in the fracture-healing process and weight-bearing function were observed in all cases. Radiographic scores at the bone connection areas and within the allograft improved significantly over time (p < 0.05). There were not any significant differences in radiographic scores between the infected and non-infected groups.

Clinical Significance Bone reconstruction with FCBA is effective in the treatment of radial and ulnar nonunion fractures associated with large bone defects, regardless of the infection status of the surgical site.

Author contributions

Shuntaro Munakata, Yasushi Hara and Nobuo Kanno contributed to conception of study, study design, acquisition of data and data analysis and interpretation. Daichi Katori, Yasuji Harada and Norihiro Muroi contributed to acquisition of data and data analysis and interpretation. Shinya Yamaguchi and Hiroyuki Akagi contributed to study design, acquisition of data and data analysis and interpretation. Kei Hayashi contributed to data analysis and interpretation. Yukari Nagahiro contributed to conception of study, study design and acquisition of data. All authors drafted and revised and approved the submitted manuscript.