A Quantitative Index Derived from ^99mTc-Pertechnetate Scintigraphy to Assist in the Diagnosis of Primary Sjogren’s Syndrome

Zusammenfassung

Eine sichere und einfache szintigraphische Technik der Diagnose des primären Sjögren-Syndroms wird erläutert, die eine relativ hohe Spezifität und Sensitivität erbringt. Bisher wurde mit brauchbarem Erfolg die Serienszintigraphie eingesetzt; die hier beschriebene Verwendung des Linearitäts-Index erbrachte jedoch bessere Ergebnisse. Bei 71 untersuchten Patienten wurde eine Sensitivität von 87% und eine Spezifität von 93% ermittelt. Somit ist dies die Methode der Wahl zur Bewertung von Patienten mit Verdacht auf primäres Sjögren-Syndrom.

Summary

A safe and simple technique is reported by which primary Sjogren’s syndrome can be detected with a relatively high specificity and sensitivity. The method of serial scintigraphy has been used with reasonable success; however, the application of the linearity index as described here produced superior results. In 71 patients investigated, a sensitivity of 87% and specificity of 93% were recorded and make this the method of choice for evaluating patients suspected of having primary Sjogren’s syndrome.

Schlüsselwörter

^99mTc-pertechnetat - Primäres Sjögren-Syndrom - Linearitäts-Index - Rheumatologie - Speicheldrüsenfunktion

Key words

⁹⁹mTc-pertechnetate - primary Sjögren’s syndrome - linearity index - rheumatology - salivary gland function

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