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Nuklearmedizin 1988; 27(02): 43-45
DOI: 10.1055/s-0038-1629501
Originalarbeiten — Original Articles
Schattauer GmbH

The Conundrum of Relaxation Times

Das Rätsel der Entspannungszeiten
S. F. Akber
1   From the Department of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, MA, USA
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Publication History

Received: 01 July 1987

in revised form: 26 November 1987

Publication Date:
05 February 2018 (online)

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The current theories of proton relaxation times fall short of explaining satisfactorily the physical and biological mechanisms responsible for the dissimilarities of relaxation behavior in normal and pathological tissues. An alternative approach to understand these mechanisms is needed. This paper advances the possibility that the dissimilarities of relaxation behavior in normal and pathological tissues is due to the consumption of paramagnetic molecular O2 dissolved in cell-associated water.

Zusammenfassung

Die physikalischen und biologischen Mechanismen, die für das unterschiedliche Relaxationsverhalten von normalem und pathologischem Gewebe verantwortlich sind, werden von den gegenwärtigen Theorien der Protonrelaxationszeiten nur unzureichend erklärt. Um diese Mechanismen zu verstehen, ist ein alternativer Ansatz notwendig. Diese Arbeit verfolgt die Möglichkeit, daß die Unterschiede im Relaxationsverhalten im normalen und pathologischen Gewebe auf die Aufnahmen von paramagnetischen Molekularen im Zellwasser gelösten O2 zurückzuführen ist.

 

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