Bildgebende Verfahren in der Diagnostik von Demenzerkrankungen

F Jessen

doi:10.1055/s-0038-1628836

Nervenheilkunde, Table of Contents

Nervenheilkunde 2010; 29(11): 758-760
DOI: 10.1055/s-0038-1628836

Kognitive Störungen

Schattauer GmbH

Bildgebende Verfahren in der Diagnostik von Demenzerkrankungen

Brain imaging in the diagnostic process of dementia

F Jessen

¹Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitätsklinikum Bonn

› Author Affiliations

Abstract

Zusammenfassung

Die zerebrale Bildgebung hat in der ätiologischen Diagnostik von Demenzerkrankungen die Funktion z. B. chirurgisch behandelbare Ursachen einer Demenz aufzudecken. Zusätzlich trägt sie zur Differenzialdiagnose von primären Demenzerkrankungen bei. Neurodegenerative Erkrankungen sind durch typische Atrophiemuster gekennzeichnet. Vaskuläre Läsionen können sensitiv mit der MRT erfasst werden. Zahlreiche neue MRT-Verfahren befinden sich in der klinischen Entwicklung. Als nuklearmedizinisches Verfahren ist insbesondere die ¹⁸F-Fluordesoxyglukose (FDG)-PET wertvoll. Die zukünftige klinische Relevanz von Amyloid-PET wird mit großer Wahrscheinlichkeit sehr hoch sein.

Summary

In the diagnostic process of dementia brain imaging is needed to detect causes of dementia that may be reversible by for example surgical interventions. Also brain imaging helps in differentiating primary causes of dementia. Neurodegenerative disorders are characterized by typical patterns of atrophy. Vascular damage can be detected sensitively with MRI. Among nuclear medicine techniques, ¹⁸F-Fluordesoxyglucose (FDG)-PET is particularly valuable. The importance of amyloid PET in clinical practice in the future will be high.

Schlüsselwörter

Demenz - Alzheimer - MRT - PET

Keywords

Dementia - Alzheimer’s disease - MRI - PET

Full Text

References

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