Have you ever heard of hibernoma? A rare but important pitfall in FDG-PET/CT

• References

• 1 Agrawal A, Nair N, Baghel NS. A novel approach for reduction of brown fat uptake on FDG PET. Br J Radiol 2009; 82: 626-631.
• 2 Baldi A, Santini M, Mellone P. et al. Mediastinal hibernoma: a case report. J Clin Pathol 2004; 57: 993-994.
• 3 Burdick MJ, Jolles PR, Grimes MM, Henry DA. Mediastinal hibernoma simulates a malignant lesion on dual time point FDG imaging. Lung Cancer 2008; 59: 391-394.
• 4 Cantisani V, Mortele KJ, Glickman JN. et al. Large retroperitoneal hibernoma in an adult male: CT imaging findings with pathologic correlation. Abdom Imaging 2003; 28: 721-724.
• 5 Chatterton BE, Mensforth D, Coventry BJ, Cohen P. Hibernoma: intense uptake seen on ^99mTc tetrofos- min and FDG positron emission tomographic scanning. Clin Nucl Med 2002; 27: 369-370.
• 6 Craig WD, Fanburg-Smith JC, Henry LR. et al. Fat- containing lesions of the retroperitoneum: radiol- ogic-pathologic correlation. Radiographics 2009; 29: 261-290.
• 7 Cypess AM, Lehman S, Williams G. et al. Identification and importance of brown adipose tissue in adult humans. N Engl J Med 2009; 360: 1509-1517.
• 8 Da Motta AC, Tunkel DE, Westra WH, Yousem DM. Imaging findings of a hibernoma of the neck. AJNR Am J Neuroradiol 2006; 27: 1658-1659.
• 9 Enzinger FM, Weiss SW. Soft tissue tumors. Mosby: 2001
• 10 Furlong MA, Fanburg-Smith JC, Miettinen M. The morphologic spectrum of hibernoma: a clinico- pathologic study of 170 cases. Am J Surg Pathol 2001; 25: 809-814.
• 11 Gery L. In discussion of M. F. Bonnel's paper. Bull Mem Anat Paris 1914; 89: 111-112.
• 12 Giblin E, Lynn D, Mortman K. Cervical hibernoma demonstrating uptake on ^99mTc lymphoscintigraphy. Clin Nucl Med 2006; 31: 694-696.
• 13 Jennings RC, Behr G. Hibernoma (granular cell lipoma). J Clin Pathol 1955; 8: 310-312.
• 14 Merkel H. On a pseudolipoma of the breast (peculiar fat tumors). Beitr Pathol Anat 1906; 39: 152-157.
• 15 Murphey MD, Carroll JF, Flemming DJ. et al. From the archives of the AFIP: benign musculoskeletal lipomatous lesions. Radiographics 2004; 24: 1433-1466.
• 16 Nishida J, Ehara S, Shiraishi H. et al. Clinical findings of hibernoma of the buttock and thigh: rare involvements and extremely high uptake of FDG-PET. Med Sci Monit 2009; 15: CS117-122.
• 17 Oller JD, Gomez JD, Kortazar JF. et al. Scapular hibernoma fortuitously discovered on myocardial perfusion imaging through ^99mTc tetrofosmin. Clin Nucl Med 2001; 26: 69-70.
• 18 Smith CS, Teruya-Feldstein J, Caravelli JF, Yeung HW. False-positive findings on ¹⁸F-FDG PET/CT: differentiation of hibernoma and malignant fatty tumour on the basis of fluctuating standardized uptake values. AJR Am J Roentgenol 2008; 190: 1091-1096.
• 19 Subramaniam RM, Clayton AC, Karantanis D, Collins DA. Hibernoma: ¹⁸F FDG PET/CT imaging. J Thorac Oncol 2007; 2: 569-670 676.