Schlaf, Table of Contents Schlaf 2015; 04(02): 78-83DOI: 10.1055/s-0038-1626135 Review Schattauer GmbH Einfluss antikonvulsiver Medikamente auf den Schlaf Epilepsie und Schlaf BARBARA FIEDLER , GERD KURLEMANN Recommend Article Abstract Buy Article Der Zusammenhang zwischen Schlaf und Epilepsie wurde schon in der Antike beobachtet. So beschrieb schon Aristoteles, dass Epilepsien bzw. epileptische Anfälle häufig während des Schlafes aufträten (1). Full Text References Literatur 1 Tempkin O. The Falling Sickness: A History of Epilepsy from the Greeks to the Beginnings of Modern Neurology. 2nd. ed. Baltimore: John Jopkins Press; 1994 2 Minecan D, Natarajan A, Marzec M, Malow B. Relationship of epileptic seizures to sleep stage and sleep depth. Sleep 2002; 25: 899-904. 3 Carpay JA, de Weerd AW, Schimsheimer RJ, Stroink H, Brouwer OF. et al. The diagnostic yield of a second EEG after partial sleep deprivation: A prospective study in children with newly diagnosed seizures. Epilepsia 1997; 38 (05) 595-599. 4 King MA, Newton MR, Jackson GD, Fitt GJ, Mitchell LA. et al. Epileptology of the first-seizure presentation: a clinical, electroencephalographic, and magnetic resonance imaging study of 300 consecutive patients. Lancet 1998; 352: 1007-1011. 5 Lüders H. Benign focal epilepsy of childhood. In: Lüders H, Lesser RP. (Hrsg.) Epilepsy-Electroclinical syndromes. London: Springer; 1987: 303-346. 6 de Weerd A, de Haas S, Otte A, Trenité DK, van Erp G, Cohen A. et al. Subjective sleep disturbance in patients with partial epilepsy: a questionnaire-based study on prevalence and impact on quality of life. Epilepsia 2004; 45: 1397-1404. 7 Krishnan P, Sinha S, Taly AB, Ramachandraiah CT, Rao S, Satishchandra P. Sleep disturbances in juvenile myoclonic epilepsy: a sleep questionnaire-based study. Epilepsy Behav 2012; 23 (03) 305-309. 8 Rocamora R, Sánchez-Alvarez JC, Salas-Puig J. The relationship between sleep and epilepsy. The Neurologist 2008; 14: S35-S43. 9 Unterberger I, Gabelia D, Prieschl M, Chea K, Hofer M, Högl B, Luef G, Frauscher B. Sleep disorders and circadian rhythm in epilepsy revisited: a prospective controlled study. Sleep Med 2015; 16: 237-242. 10 van Golde EGA, Gutter T, de Weerd AW. Sleep disturbances in people with epilepsy: prevalence, impact and treatment. Sleep Med Rev 2011; 15: 357-368. 11 Zanzmera P, Shukla A. Gupta, et al. Markedly disturbed sleep in medically refractory compared to controlled epilepsy – a clinical and polysomnography study. Seizure 2012; 21 (07) 487-490. 12 Riemann D, Gann H, Hohagen F. et al. The effect of carbamazepine on endocrine and sleep EEG variables in a patient with 48-hour rapid cycling, and healthy controls Neuropsychobiology. 1993; 27: 163-170. 13 Yang JD, Elphick M, Sharpley AL. et al. Effects of carbamazepine on sleep in healthy volunteers. Biol Psychiatry 1989; 26: 324-328. 14 Gann H, Riemann D, Hohagen F. et al. The influence of carbamazepine on sleep-EEG and the clonidine test in healthy subjects: results of a preliminary study. Biol Psychiatry 1994; 35: 893-896. 15 Cicolin A, Magliola U, Giordano A. et al. Effects of levetiracetam on nocturnal sleep and daytime vigilance in healthy volunteers. Epilepsia 2006; 47: 82-85. 16 Obermeyer WH, Benca RM. Effects of drugs on sleep. Neurol Clin 1996; 14: 827-842. 17 Salinsky MC, Oken BS, Binder LM. Assessment of drowsiness in epilepsy patients receiving chronic antiepileptic drug therapy. Epilepsia 1996; 37: 181-187. 18 Sanders MH. Medical therapy for sleep apnea. In: Kryger MH, Roth T, Dement WC. editors. Principles and practice of sleep medicine. Philadelphia (PA): WB Saunders Co.; 1994: 678-693. 19 Seibt J, Aton SJ, Jha SK, Coleman T, Dumoulin MC, Frank MG. The non-benzodiazepine hypnotic zolpidem impairs sleep-dependent cortical plasticity. Sleep 2008; 31 (10) 1381-1391. 20 Harding CF, Alford CA, Powell TE. The effect of sodium valproate on sleep, reaction times, and visual evoked potential in normal subjects. Epilepsia 1985; 26: 597-601. 21 Foldyary-Schaefer N. Sleep complaints and epilepsy: the role of seizures, antiepileptic drugs and sleep disorders. J Clin Neurophyiol 2002; 19: 514-521. 22 Zhang H, Yuechun L, Xiue L. et al., Effect of sodium valproate on the sleep stuctures of epileptic patients. Exp and Therapeut Med 2014; 7: 1227-1232. 23 Gigli GL, Placidi F, Diomedi M. et al. Nocturnal sleep and daytime somnolence in untreated patients with temporal lobe epilepsy: changes after treatment with controlled-release carbamazepine. Epilepsia 1997; 38: 696-701. 24 Foldvary N, Perry M, Lee J. et al. The effects of lamotrigine on sleep in patients with epilepsy. Epilepsia 2001; 42: 1569-1573. 25 Placidi F, Marciani MG, Diomedi M. et al. Effects of lamotrigine on nocturnal sleep, daytime somnolence and cognitive functions in focal epilepsy. Acta Neurol Scand 2000; 102: 81-86. 26 Sadler M. Lamotrigine associated with insomnia. Epilepsia 1999; 40: 322-325. 27 Bell C, Vanderlinden H, Hiersemenzel R. et al. The effects of levetiracetam on objective and subjective sleep parameters in healthy volunteers and patients with partial epilepsy. J Sleep Res 2002; 11: 255-263. 28 Hindmarch I, Dawson J, Stanley N. A double-blind study in healthy volunteers to assess the effect on sleep of pregabalin compared with aprazolam and placebo. Sleep 2005; 28: 187-193. 29 Bazil CW, Dave J, Cole J. et al. Pregabalin increases slow-wave sleep and may improve attention in patients with partial epilepsy and insomnia. Epilepsy & Behaviour 2012; 23: 422-425. 30 Roth T, Arnold LM, Garcia-Borreguero D. et al. A review of the effects of pregabalin on sleep disturbance across multiple clinical conditions. Sleep Med Rev 2014; 18: 261-271. 31 Romigi A, Izzi F, Placidi F. et al. Effects of zonisamide as add-on therapy on sleep-wake cycle in focal epilepsy: A polysomnographic study. Epilepsy & Behavior 2013; 26: 170-174.