CC-BY-NC-ND 4.0 · AJP Rep 2018; 08(01): e13-e17
DOI: 10.1055/s-0038-1625974
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Pre-pregnancy Body Mass Index and Third-Trimester Depressive Symptoms in a Healthy Privately Insured Sample

Stephanie A. Schuette
1  Department of Psychology and Neuroscience, Duke University, Durham, North Carolina
,
Michelle A. Kominiarek
2  Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois
,
Katherine L. Wisner
2  Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois
3  Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois
,
Suena H. Massey
3  Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois
4  Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois
› Author Affiliations
Funding This work was supported by a grant from the Evergreen Invitational Women's Health Grants Initiative of the Northwestern Memorial Foundation (NMF) to Dr. Massey, grant 5K23DA037913 from the National Institute on Drug Abuse (NIDA) of the National Institutes of Health (NIH) to Dr. Massey, and grant K23HD076010 from the Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) of the NIH to Dr. Kominiarek. The NMF, NIDA, NICHD, and NIH had no role in the study design, collection, analysis or interpretation of data, writing of the article, or the decision to submit this article for publication.
Further Information

Publication History

23 June 2017

09 December 2017

Publication Date:
05 February 2018 (online)

Abstract

Objectives While being overweight (body mass index [BMI] >25) prior to pregnancy is linked to antenatal depression, whether weight is confounded by socioeconomic and/or medical risks is unclear.

Study Design We assessed 66 healthy privately insured pregnant women at M = 35.0 ± 3.3 weeks for symptoms of depression (Inventory for Depressive Symptoms—Self-Report (IDS-SR 30), lifetime history of depression and other psychiatric conditions (Mini International Neuropsychiatric Interview), and pre-pregnancy BMI derived from pre-pregnancy weight (by recall) and directly measured height. Pre-pregnancy overweight (BMI > 25) and antenatal depression (score of mild or greater [14] on the IDS-SR 30) were assessed using logistic regression, controlling for past major depressive disorder (MDD) and demographic factors showing significant between group differences.

Results Pre-pregnancy overweight (n = 17; 25.8%) was associated with an increased risk of third trimester depression, independent of past MDD and marital status (odds ratio = 7.47; 95% confidence interval [2.09–26.68]; B (standard error) = 2.010 [0.650]).

Conclusion Replication in a larger sample is suggested to confirm an independent effect of pregravid overweight on third trimester depression.