Therapie eines Plattenepithelkarzinoms im Bereich des dritten Augenlids bei einem Pferd mittels Iridium-192-Implantaten

Zusammenfassung:

Gegenstand und Ziel: Beschreibung von klinischem Erscheinungsbild, Diagnostik, Therapie sowie einer 27 Monate dauernden Verlaufsuntersuchung eines Plattenepithelkarzinoms des dritten Augenlids bei einem Pferd. Material und Methoden: Ein siebenjähriger Haflinger-Wallach wurde mit einer progressiv wachsenden Umfangsvermehrung im Bereich des rechten dritten Augenlids in der Klinik vorgestellt. Unter Allgemeinanästhesie erfolgte die chirurgische Exzision des rechten dritten Augenlids. Zwei Iridium- 192-Stäbe wurden subkutan im Bereich des rechten nasalen Augenwinkels in das Ober- und Unterlid eingebracht. Ergebnisse: Das Pferd zeigte keinerlei therapiebedingte Komplikationen. Innerhalb von 27 Monaten nach der Behandlung trat kein Rezidiv auf. Schlussfolgerungen: Das Plattenepithelkarzinom des dritten Augenlids kann bei rechtzeitiger Therapie erfolgreich mittels chirurgischer Exzision und interstitieller Brachytherapie behandelt werden. Klinische Relevanz: Die interstitielle Brachytherapie in Kombination mit einer chirurgischen Tumorexzision kann eine Therapieform des periokulären Plattenepithelkarzinoms mit Langzeiterfolg darstellen. Die Durchführung der interstitiellen Brachytherapie ist Spezialkliniken vorbehalten.

Summary:

Objective: Description of clinic, diagnosis, therapy (i. e. tumour excision) in combination with interstitial brachytherapy and follow-up of a squamous cell carcinoma of the nictitating membrane in a horse. Material and methods: A seven-year-old Haflinger gelding was referred with a progressively increasing mass of the right nictitating membrane. Surgical excision of the right nictitating membrane was performed under general anaesthesia. Following temporary tarsorrhaphy two iridium-192 pins were implanted in the subcutaneous tissue of the upper and lower eyelid at the level of the nasal eye-angle. Results: No therapy-related adverse reactions were noted. Follow-up of 27 months revealed no local recurrence of the tumour. Conclusion: Squamous cell carcinoma of the nictitating membrane can be successfully treated with surgical tumour excision combined with interstitial brachytherapy. Clinical relevance: Interstitial brachytherapy in combination with surgical tumor excision can be a therapeutic method of the periocular squamous cell carcinoma with a good long-term success rate. Interstitial brachytherapy must be performed in spezialized clinics.

Schlüsselwörter:

Pferd - Haflinger - Plattenepithelkarzinom - Brachytherapie - drittes Augenlid

Key words:

Horse - Haflinger - squamous cell carcinoma - brachytherapy - nictitating membrane

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