Semin Neurol 2018; 38(01): 032-040
DOI: 10.1055/s-0037-1618600
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Radiomics, Metabolic, and Molecular MRI for Brain Tumors

Philipp Kickingereder
1  Department of Neuroradiology, University of Heidelberg Medical Center, Heidelberg, Germany
Ovidiu Cristian Andronesi
2  Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
› Author Affiliations
Further Information

Publication History

Publication Date:
16 March 2018 (online)


Magnetic resonance imaging plays a key role in diagnosis and treatment monitoring of brain tumors. Novel imaging techniques that specifically interrogate aspects of underlying tumor biology and biochemical pathways have great potential in neuro-oncology. This review focuses on the emerging role of 2-hydroxyglutarate-targeted magnetic resonance spectroscopy, as well as radiomics and radiogenomics in establishing diagnosis for isocitrate dehydrogenase mutant gliomas, and for monitoring treatment response and predicting prognosis of this group of brain tumor patients.