CC BY-NC-ND 4.0 · Int Arch Otorhinolaryngol 2019; 23(01): 104-109
DOI: 10.1055/s-0037-1617427
Systematic Review
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Otomyiasis: Systematic Review

María Teresa Rodríguez-Ruiz
1   Department of Emergency, Hospital Universitario San Ignacio, Facultad de Medicina de la Pontificia Universidad Javeriana, Bogotá, Colombia
,
Ana María Acosta
2   Departament Otolaryngology, Facultad de Medicina de la Pontificia Universidad Javeriana, Bogotá, Colombia
,
Eduardo Cifuentes-Cardozo
1   Department of Emergency, Hospital Universitario San Ignacio, Facultad de Medicina de la Pontificia Universidad Javeriana, Bogotá, Colombia
,
María Alejandra Chirveches
3   Department of Clinical Epidemiology and Biostatistics, Facultad de Medicina de la Pontificia Universidad Javeriana, Bogotá, Colombia
,
Diego Rosselli
3   Department of Clinical Epidemiology and Biostatistics, Facultad de Medicina de la Pontificia Universidad Javeriana, Bogotá, Colombia
› Institutsangaben
Weitere Informationen

Publikationsverlauf

27. Juli 2017

15. November 2017

Publikationsdatum:
13. März 2018 (online)

Abstract

Introduction Myiasis is a disease caused by fly larvae that grow in the tissues of animals and humans. It can cause a variety of local symptoms, like erythema or pain, depending on its location, and generalized symptomatology, such as fever and malaise. Myiasis can generate severe complications, for instance sepsis, or directly impact vital tissues. Its management varies depending on the location, and on the preferences of the doctor that faces this challenge. Myiasis usually occurs in tropical countries, and, in many places, it is not a rare condition. The cases are rarely reported, and there are no published management protocols.

Objective To review the literature regarding the most common agents, the predisposing factors and the treatment alternatives for otic myiasis, a rare form of human myiasis caused by the infestation of fly larvae in the ear cavities.

Data synthesis We present a systematic review of the literature. The search in five databases (Medline, Embase, Cochrane Database of Systematic Reviews, LILACS and RedALyC) led to 63 published cases from 24 countries, in the 5 continents. The ages of the patients ranged from newborn to 65 years old. The most common agents belong to the Sarcophagidae or Calliphoridae families. Chronic otitis media, previous otic surgical procedures, mental deficit, alcohol or drug abuse, sleeping outdoors, prostration, and malnutrition were predisposing factors. The treatment alternatives are herein discussed.

Conclusion The results highlight the need for monitoring, follow-up and standardization of medical approaches.

Note

All authors contributed equally to this work.


 
  • References

  • 1 Hope FW. On insects and their larvae occasionally found in the human body. Trans Entomol Soc. 1840; 2: 256-271
  • 2 The Joanna Briggs Institute. Reviewer's Manual. Australia: The Joanna Briggs Institute; 2014
  • 3 Centre for Evidence-Based Management. Critical appraisal of a survey. [updated 2014 June 5]. Available from: http://www.cebma.org/wp-content/uploads/Critical-Appraisal-Questions-fora-Survey.pdf
  • 4 Moher D, Liberati A, Tetzlaff J, Altman DG. ; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 2009; 151 (04) 264-269 , W64
  • 5 Yuca K, Caksen H, Sakin YF. , et al. Aural myiasis in children and literature review. Tohoku J Exp Med 2005; 206 (02) 125-130
  • 6 Villamizar J, Sandoval G. Miasis ótica. Acta Otorrinolaringol Cir Cabeza Cuello. 2000; 28 (03) 203-206
  • 7 Ahmad NW, Ismail A, Jeffery J. , et al. Aural myiasis in a neonate in peninsular Malaysia. Parasit Vectors 2009; 2 (01) 63
  • 8 Akduman D, Arslan MO, Gul S. A case of otomyiasis in a child with chronic otitis media. Int J Pediatr Otorhinolaryngology Extra 2011; 6 (03) 116-118
  • 9 Bayindir T, Miman O, Miman MC, Atambay M, Saki CE. Bilateral aural myiasis (Wohlfahrtia magnifica): a case with chronic suppurative otitis media. Turkiye Parazitol Derg 2010; 34 (01) 65-67
  • 10 Al Jabr I. Aural myiasis, a rare cause of earache. Case Rep Otolaryngol 2015; 2015: 219529
  • 11 Bowe Douglas L, Amaro Trapaga E, Sotolongo Guerra F, Alonso Bermudez P. [Otic myiasis in a newborn caused by Calliphoridae larvae of the genus Phaenicia]. Rev Cubana Med Trop 1977; 29 (02) 75-79
  • 12 Calderón O, Rivera P, Sánchez C, Solano M. Cochliomyia hominivorax (diptera; calliphoridae) como agente causal de miasis aural en un niño de Costa Rica. Parasitol. 1996; 20 (34) 130-132
  • 13 Calvo LM, Suárez MM, Apolinario RM, Martín AM. [Larvae in the external auditory canal and nasal fossae of an alcoholic patient]. Enferm Infecc Microbiol Clin 2005; 23 (05) 323-324
  • 14 Casanova-Roman M, Sanchez-Legaza E, Sanchez-Porto A, Murga C. Aural myiasis in an infant. Infez Med 2010; 18 (03) 175-176
  • 15 Çetinkaya M, Özkan H, Köksal N, Coşkun SZ, Hacimustafaoğlu M, Girişgin O. Neonatal myiasis: a case report. Turk J Pediatr 2008; 50 (06) 581-584
  • 16 Kaczmarczyk D, Kopczyński J, Kwiecień J, Michalski M, Kurnatowski P. The human aural myiasis caused by Lucilia sericata. Wiad Parazytol 2011; 57 (01) 27-30
  • 17 Chaiwong T, Tem-Eiam N, Limpavithayakul M, Boongunha N, Poolphol W, Sukontason KL. Aural myiasis caused by Parasarcophaga (Liosarcophaga) dux (Thomson) in Thailand. Trop Biomed 2014; 31 (03) 496-498
  • 18 Cho JH, Kim HB, Cho CS, Huh S, Ree HI. An aural myiasis case in a 54-year-old male farmer in Korea. Korean J Parasitol 1999; 37 (01) 51-53
  • 19 Cunningham DG, Zanga JR. Myiasis of the external auditory meatus. J Pediatr 1974; 84 (06) 857-858
  • 20 Davies DM. Human aural myiasis: a case in Ontario, Canada, and a partial review. J Parasitol 1976; 62 (01) 124
  • 21 González Poggioli N, Vázquez Barro JC. [Otic myiasis. Case report]. Acta Otorrinolaringol Esp 2009; 60 (03) 213-214
  • 22 Hatten K, Gulleth Y, Meyer T, Eisenman DJ. Myiasis of the external and middle ear. Ann Otol Rhinol Laryngol 2010; 119 (07) 436-438
  • 23 Iqbal Z, Sharma S, Sami H, Kumar A. Unusual pseudomyiasis with Musca domestica (housefly) larvae in a child with chronic otitis media. Indian J Otolaryngol 2016; 22 (02) 132-134
  • 24 Karaman E, Samasti M, Saritzali G, Ozdemir S, Halil MC, Isildak H. Otomyiasis by Wohlfahrtia magnifica. J Craniofac Surg 2009; 20 (06) 2123-2124
  • 25 LaCourse SM, Martinez RM, Spach DH, Fang FC. Pain and bloody ear discharge in a returning traveler. Am J Trop Med Hyg 2015; 92 (03) 599-600
  • 26 Lee HL, Yong YK. Human aural myiasis. Southeast Asian J Trop Med Public Health 1991; 22 (02) 274-275
  • 27 Magliulo G, Gagliardi M, D'Amico R. Human aural myiasis. Otolaryngol Head Neck Surg 2000; 122 (05) 777
  • 28 Maturo S, Michaelson PG, Horlbeck D, Brennan J. Auricular myiasis. Otolaryngol Head Neck Surg 2007; 136 (04) 668-669
  • 29 Mendivil JA, El Shammaa NA. Aural myiasis caused by Cochliomyia hominivorx: case report. Mil Med 1979; 144 (04) 261-262
  • 30 Menghi CI, Gatta CL, Oliva A. [Otomyiasis by Cochliomyia hominivorax in two children from the outskirts of Buenos Aires, Argentina]. Rev Argent Microbiol 2010; 42 (03) 176-178
  • 31 Morris B. First reported case of human aural myiasis caused by the flesh fly Parasarcophaga crassipalpis (Diptera: Sarcophagidae). J Parasitol 1987; 73 (05) 1068-1069
  • 32 Neira P, Muñoz N, Cantero D. [Auricular myiasis cause by Cochliomyia hominivorax (Diptera: Calliphoridae) (Coquerel, 1858)]. Rev Med Chil 2002; 130 (08) 907-909
  • 33 Olatoke F, Afolabi O, Lasisi O, Alabi B, Aluko A. Aural myiasis: Case report from Nigeria. Int J Pediatr Otorhinolaryngology Extra 2011; 6 (04) 233-234
  • 34 Olteanu AI, Enescu A. [Otic myiasis. Clinical and parasitological considerations]. Rev Chir Oncol Radiol O R L Oftalmol Stomatol Otorinolaringol 1979; 24 (02) 139-144
  • 35 Panu F, Cabras G, Contini C, Onnis D. Human auricolar myiasis caused by Wohlfartia magnifica (Schiner) (Diptera: Sarcophagidae): first case found in Sardinia. J Laryngol Otol 2000; 114 (06) 450-452
  • 36 Rohela M, Jamaiah I, Amir L, Nissapatorn V. A case of auricular myiasis in Malaysia. Southeast Asian J Trop Med Public Health 2006; 37 (03) (Suppl. 03) 91-94
  • 37 Sharan R, Isser DK. Aural myiasis. J Laryngol Otol 1978; 92 (08) 705-708
  • 38 Talari S, Yeganeh-moghadam A, Dehghani R. Chrysomya bezziana infestation. Arch Iran Med 2002; 5 (01) 56-58
  • 39 Tligui H, Bouazzaoui A, Agoumi A. [Human auricular myiasis caused by Wohlfahrtia magnifica (Diptera: Sarcophagidae): about three observations in Morocco]. Bull Soc Pathol Exot 2007; 100 (01) 61-64
  • 40 Uzun L, Cinar F, Beder LB, Aslan T, Altintas K. Radical mastoidectomy cavity myiasis caused by Wohlfahrtia magnifica. J Laryngol Otol 2004; 118 (01) 54-56
  • 41 Werminghaus P, Hoffmann TK, Mehlhorn H, Bas M. Aural myiasis in a patient with Alzheimer's disease. Eur Arch Otorhinolaryngol 2008; 265 (07) 851-853
  • 42 Yaghoobi R, Tirgari S, Sina N. Human auricular myiasis caused by Lucilia sericata: Clinical and parasitological considerations. Acta Med Iran 2005; 43 (02) 155-157
  • 43 Yazgi H, Uyanik MH, Yoruk O, Aslan I. Aural myiasis by Wohlfahrtia magnifica: Case Report. Eurasian J Med 2009; 41 (03) 194-196
  • 44 Manuel Martín A, Montes I, Domínguez De Luis F. External otitis due to fly larvas. Enferm Infecc Microbiol Clin 2001; 19 (08) 403-405
  • 45 West JK. Simple and effective field extraction of human botfly, Dermatobia hominis, using a venom extractor. Wilderness Environ Med 2013; 24 (01) 17-22
  • 46 Gallego J, Gallego M. Infecciones causadas por artrópodos. En: Farreras Valenti P, Rozman C. Medicina Interna. 14 ed. Madrid: Harcourt; 2001: 2800-2802
  • 47 Jervis-Bardy J, Fitzpatrick N, Masood A, Crossland G, Patel H. Myiasis of the ear: a review with entomological aspects for the otolaryngologist. Ann Otol Rhinol Laryngol 2015; 124 (05) 345-350
  • 48 McGraw TA, Turiansky GW. Cutaneous myiasis. J Am Acad Dermatol 2008; 58 (06) 907-926 , quiz 927–929
  • 49 Dourmishev AL, Dourmishev LA, Schwartz RA. Ivermectin: pharmacology and application in dermatology. Int J Dermatol 2005; 44 (12) 981-988
  • 50 Osorio J, Moncada L, Molano A, Valderrama S, Gualtero S, Franco-Paredes C. Role of ivermectin in the treatment of severe orbital myiasis due to Cochliomyia hominivorax. Clin Infect Dis 2006; 43 (06) e57-e59