50 Jahre GTH – Erwartungen, Erfolge, Enttäuschungen

K. Lechner

doi:10.1055/s-0037-1616870

Hämostaseologie, Inhaltsverzeichnis

Hamostaseologie 2006; 26(01): 5-12
DOI: 10.1055/s-0037-1616870

Original article

Schattauer GmbH

50 Jahre GTH – Erwartungen, Erfolge, Enttäuschungen

Eine persönliche Perspektive50 years GTH – expectations, progress, disappointmentsA personal perspective

K. Lechner

Abstract

Zusammenfassung

Die Deutsche Arbeitsgemeinschaft für Blutgerinnungsforschung (DAB) wurde 1956 gegründet und 1982 in die Gesellschaft für Thrombose und Hämostase (GTH), eine multinationale, vorwiegend deutschsprachige Gesellschaft umgewandelt. In den letzten vier Dekaden (seit meiner Tätigkeit auf diesem Gebiet) war der Fortschritt der Grundlagenforschung enorm, der Fortschritt in Diagnostik und Therapie auf den verschiedenen Teilgebieten der Hämostaseologie unterschiedlich. Die größten Fortschritte waren die Herstellung effektiver und infektionssicherer Faktor-VIII- und -IXKonzentrate, die Entdeckung thrombophiler Diathesen, die Einführung nicht invasiver bildgebender Verfahren zur Diagnostik venöser Thromboembolien und die Diagnostik und Therapie immunologisch bedingter Koagulopathien. Die vergangenen Jahrzehnte waren auch geprägt durch Versuche, die Diagnostik und Therapie, insbesondere bei thromboembolischen Erkrankungen zu optimieren und standardisieren (evidence-based medicine). Trotzdem sind Diagnostik und Therapie individuell in vielen Fällen immer noch schwierig, was die Beratung durch einen auf diesem Gebiet spezialisierten Fachmann (Hämostaseologen) erforderlich macht.

Summary

The Deutsche Arbeitsgemeinschaft für Blutgerinnungsforschung (DAB) (German Working Party on Blood Coagulation) was founded in 1956 by a few German specialists in haemostasis. In 1982, the DAB was replaced by the Society on Thrombosis and Haemostasis (GTH), which was multinational, with emphasis on German speaking countries. Since I started in this field there was steady progress in the diagnosis and treatment of haemorrhagic and thrombotic disorders. Milestones were the production of effective and safe factor VIII and IX concentrates for haemophilia treatment, the diagnosis of venous thromboembolic disorders by non-invasive methods, the definition of thrombophilic states by laboratory methods and the diagnosis and treatment of immune coagulopathies. In other fields, progress was less impressive.

During the last decades attempts have been made to optimize and standardize diagnosis and treatment in the thrombosis and haemostasis field (evidence based medicine). Despite guidelines and consensus statements the clinical problems in individual patients are still frequent and considerable. Therefore, physicians with a special expertise in the field of thrombosis and haemostasis are needed.

Schlüsselwörter

Hämophilie - venöse Thromboembolie - Thrombozyten

Keywords

Haemophilia - venous thromboembolism - platelet disorders

Volltext

Referenzen

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