Download PDF
Thromb Haemost 2005; 93(04): 787-788
DOI: 10.1055/s-0037-1616784
Case Report
Schattauer GmbH

HELLP syndrome with fetal growth retardation in a woman homozygous for the prothrombin gene variant 20210A

Georg Moessmer
1   Institute for Clinical Chemistry, Technische Universität München, Klinikum rechts der Isar, München, Germany
,
Burkhardt Müller
1   Institute for Clinical Chemistry, Technische Universität München, Klinikum rechts der Isar, München, Germany
,
Martin Kolben
2   Department of Obstetrics and Gynaecology, Technische Universität München, Klinikum rechts der Isar, München, Germany
,
Manfred Schmitt
2   Department of Obstetrics and Gynaecology, Technische Universität München, Klinikum rechts der Isar, München, Germany
,
Karl Theodor Maria Schneider
2   Department of Obstetrics and Gynaecology, Technische Universität München, Klinikum rechts der Isar, München, Germany
,
Almut Artmann
2   Department of Obstetrics and Gynaecology, Technische Universität München, Klinikum rechts der Isar, München, Germany
› Author Affiliations
Further Information

Publication History

Received 27 July 2004

Accepted after resubmission 13 January 2005

Publication Date:
15 December 2017 (online)

    Permissions and Reprints

 

 

  • References

  • 1 American College of Obstetricians and Gynecologists. Hypertension in pregnancy. ACOG Technical Bulletin no 219. Washington DC: American College of Obstetricians and Gynecologists, 1996. (also published in: Int J Gynecol Obstet 1996; 53: 175-83.
    PubMedGoogle Scholar
  • 2 Kupferminc MJ, Eldor A, Steinman N. et al. Increased frequency of genetic thrombophilia in women with complications of pregnancy. N Engl J Med 1999; 340: 9-13.
    CrossrefPubMedGoogle Scholar
  • 3 Kupferminc MJ, Fait G, Many A. et al. Severe preeclampsia and high frequency of genetic thrombophilic mutations. Obstet Gynecol 2000; 96: 45-9.
    PubMedGoogle Scholar
  • 4 Van Pampus MG, Dekker GA, Wolf H. et al. High prevalence of hemostatic abnormalities in women with a history of severe preeclampsia. Am J Obstet Gynecol 1999; 180: 1146-50.
    CrossrefPubMedGoogle Scholar
  • 5 De Groot CJM, Bloemenkamp KWM, Duvekot EJ. et al. Preeclampsia and genetic risk factors for thrombosis: A case-control study. Am J Obstet Gynecol 1999; 181: 975-80.
    CrossrefPubMedGoogle Scholar
  • 6 Livingston JC, Barton JR, Park V. et al. Maternal and fetal inherited thrombophilias are not related to the development of severe preeclampsia. Am J Obstet Gynecol 2001; 185: 153-7.
    CrossrefPubMedGoogle Scholar
  • 7 D´Aniello G, Florio P, Sabatini L. et al. The search for thrombophilic gene mutations in women with gestational hypertension does not help in predicting poor pregnancy outcome. J Hypertens 2003; 21: 1915-20.
    CrossrefPubMedGoogle Scholar
  • 8 Tempfer CB, Jirecek S, Riener EK. et al. Polymorphisms of thrombophilic and vasoactive genes and severe preeclampsia: a pilot study. J Soc Gynecol Investig 2004; 11: 227-31.
    CrossrefPubMedGoogle Scholar
  • 9 Poort SR, Rosendaal FR, Reitsma PH. et al. A common genetic variation in the 3´-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996; 88: 3698-703.
    CrossrefPubMedGoogle Scholar