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Thromb Haemost 2001; 86(03): 935-936
DOI: 10.1055/s-0037-1616160
Letters to the Editor
Schattauer GmbH

Nature of the Fibrinogen Aα Gene TaqI Polymorphism

Jasper A. Remijn
1   Thrombosis and Haemostasis Laboratory, Department of Haematology
,
Richard van Wijk
2   Department of Clinical Chemistry, University Medical Center, Utrecht, The Netherlands
,
Philip G. de Groot
1   Thrombosis and Haemostasis Laboratory, Department of Haematology
,
Wouter W. van Solinge
2   Department of Clinical Chemistry, University Medical Center, Utrecht, The Netherlands
› Institutsangaben
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Publikationsverlauf

Received 27. März 2001

Accepted 03. Mai 2001

Publikationsdatum:
14. Dezember 2017 (online)

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  • References

  • 1 Al-Mondhiry H, Ehmann WC. Congenital afibrinogenemia. Am J Hematol 1994; 46: 343-7.
    CrossrefPubMedGoogle Scholar
  • 2 Remijn JA, Wu YP, IJsseldijk MJW, Zwaginga JJ, Sixma JJ, de Groot PG. Absence of fibrinogen in afibrinogenemia results in large but loosely packed thrombi under flow conditions. Thromb Haemost 2001; 85: 736-42.
    Artikel in Thieme ConnectPubMedGoogle Scholar
  • 3 Humphries SE, Imam AMA, Robbins TP, Cook M, Carritt B, Ingle C, Williamson R. The identification of a DNA polymorphism of the α fibrinogen gene and the regional assignment of the human fibrinogen genes to 4q26-qter. Hum Genet 1984; 68: 148-53.
    CrossrefPubMedGoogle Scholar
  • 4 Thomas A, Lamlum H, Humphries S, Green F. Linkage disequilibrium across the fibrinogen locus as shown by five genetic polymorphisms, G/A-455 (HaeIII), C/T-148 (HindIII/AluI), T/G+1689 (AvaII), and BclI (β-fibrinogen) and TaqI (α-fibrinogen) and their detection by PCR. Hum Mut 1994; 3: 79-81.
    CrossrefPubMedGoogle Scholar
  • 5 Grieninger G, Lu X, Cao Y, Fu Y, Kudryk BJ, Galanakis DK, Hertzberg KM. Fib420, the novel fibrinogen subclass: newborn levels are higher than adult. Blood 1997; 90: 2609-14.
    CrossrefPubMedGoogle Scholar
  • 6 Humphries SE, Cook M, Dubowitz M, Stirling Y, Meade TW. Role of genetic variation at the fibrinogen locus in determination of plasma fibrinogen concentrations. Lancet 1987; 1452-5.
    PubMedGoogle Scholar
  • 7 Connor JM, Fowkes FGR, Wood J, Smith FB, Donnan PT, Lowe GDO. Genetic variation at fibrinogen loci and plasma fibrinogen levels. J Medical Genetics 1992; 29: 480-2.
    PubMedGoogle Scholar
  • 8 Rauramaa R, Väisänen S, Nissinen A, Rankinen T, Penttilä I, Saarikoski S, Tuomilehto J, Gagnon J, Pérusse L, Bouchard C. Physical activity, fibrinogen plasma level and gene polymorphisms in postmenopausal women. Thromb Haemost 1997; 78: 840-4.
    Artikel in Thieme ConnectPubMedGoogle Scholar
  • 9 Doggen CJM, Bertina RM, Manger Cats V, Rosendaal FR. Fibrinogen polymorphisms are not associated with the risk of myocardial infarction. Br J Haematol 2000; 110: 935-8.
    CrossrefPubMedGoogle Scholar
  • 10 Oksanen L, Kaprio J, Mustajoki P, Kontula K. A common pentanucleotide polymorphism of the 3′-untranslated part of the leptin receptor gene generates a putative stem-loop motif in the mRNA and is associated with serum insulin levels in obese individuals. Int J Obes Relat Metab Disord 1998; 22: 634-40.
    CrossrefPubMedGoogle Scholar