Prevalence of the C536T Mutation in the Tissue Factor Pathway Inhibitor (TFPI) Gene among Patients with Venous Thromboembolic Disease

Thromb Haemost 2001; 85(05): 938-939
DOI: 10.1055/s-0037-1615774

Letters to the Editor

Schattauer GmbH

Katia Paciaroni

¹Department of Hematology, Catholic University, Rome, Italy

,

Elena Rossi

¹Department of Hematology, Catholic University, Rome, Italy

,

Mario Bazzan

²Service of Hematology, Ospedale Evangelico Valdese, Torino, Italy

,

Helen Ireland

³Department of Hematology, Charing Cross Hospital, Hammersmith, London, United Kingdom

,

Valerio De Stefano

¹Department of Hematology, Catholic University, Rome, Italy

References
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2 Kleesiek K, Schmidt M, Gotting C, Brinkmann T, Prohaska W. A first mutation in the human tissue factor pathway inhibitor gene encoding [P151L] TFPI. Blood 1998; 92: 3976-7.
3 Kleesiek K, Schmidt M, Gotting C, Schwenz B, Lange S, Muller-Berghaus G, Brinkmann T, Prohaska W. The 536C→T transition in the human tissue factor pathway inhibitor (TFPI) gene is statistically associated with a higher risk for venous thrombosis. Thromb Haemost 1999; 82: 1-5.
4 Evans GD, Langdown J, Brown K, Baglin TP. The C536T transition in the Tissue Factor Pathway Inhibitor gene is not a common cause of venous thromboembolic disease in the UK population. Thromb Haemost 2000; 83: 5 .
5 Gonzalez-Conejero R, Lozano ML, Corral J, Martinez C, Vicente V. The TFPI 536C →■ T mutation is not associated with increased risk for venous or arterial thrombosis. Thromb Haemost 2000; 83: 787-8.
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