CC BY-NC-ND 4.0 · Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery 2018; 37(01): 42-46
DOI: 10.1055/s-0037-1615257
Case Report | Relato de Caso
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Low-grade Endometrial Stromal Sarcoma with Unusual Metastasis to the Skull

Sarcoma endometrial estromal de baixo grau com metástase incomum no crânio
Antonio Santos de Araújo Júnior
1   Department of Neurosurgery, Hospital Sírio-libanês, São Paulo, SP, Brazil
,
Pedro Alberto Arlant
1   Department of Neurosurgery, Hospital Sírio-libanês, São Paulo, SP, Brazil
,
Arnaldo Salvestrini Júnior
1   Department of Neurosurgery, Hospital Sírio-libanês, São Paulo, SP, Brazil
,
Angelo Fernandez
2   Department of Thoracic Surgery, Hospital Sírio-libanês, São Paulo, SP, Brazil
,
Marcos Fernando de Lima Docema
3   Department of Neuroradiology, Hospital Sírio-libanês, São Paulo, SP, Brazil
,
Rômulo Loss Mattedi
4   Department of Pathology, Hospital Sírio-libanês, São Paulo, SP, Brazil
,
Thales Parenti Silveira
4   Department of Pathology, Hospital Sírio-libanês, São Paulo, SP, Brazil
,
José Guilherme Mendes Pereira Caldas
5   Department of Interventional Neuroradiology, Hospital Sírio-libanês, São Paulo, SP, Brazil
,
Mirella Martins Fazzito
6   Department of Neurology, Hospital Sírio-libanês, São Paulo, SP, Brazil
› Author Affiliations
Further Information

Publication History

21 July 2017

13 November 2017

Publication Date:
15 December 2017 (online)

Abstract

Background Endometrial stromal sarcomas (ESSs) are the second most common uterine sarcomas. Although ESSs are often indolent, they have metastatic potential. To the best of our knowledge, there are only three reports of brain metastasis, and the present report is the first to describe a late skull metastasis of an ESS.

Case Report We describe the case of a 51-year-old woman who presented abnormal vaginal bleeding 14 years ago; she was diagnosed with an uterine mass and submitted to a hysterectomy. One year ago she presented ESS lung metastasis followed by a left parietal calvarial metastasis. The optimal treatment for metastatic ESS is controversial, but the use of progesterone and aromatase inhibitors is advisable.

Resumo

Introdução Sarcoma endometrial estromal (SEE) é a segunda lesão mais frequente dentre os sarcomas uterinos. Geralmente são lesões indolentes, mas com potencial de desenvolver metástase. Até o momento há apenas três relatos de metástase cerebral, sendo este o primeiro estudo a descrever uma metástase craniana tardia dessas lesões.

Relato de caso Nós descrevemos o caso de uma paciente de 51 anos de idade que apresentou há 14 anos um quadro de sangramento vaginal anormal, sendo diagnosticada uma massa uterina; a paciente foi submetida a uma histerectomia. Há um ano ela evoluiu com metástase pulmonar, seguida por metástase craniana parietal esquerda. O tratamento ideal do SEE metastático ainda é controverso, mas o uso de inibidores de aromatase é aconselhável.

Informed Consent

The patient has consented to the submission of this case report to the journal.


 
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