Superficial Vein Thrombosis: Incidence in Association with Pregnancy and Prevalence of Thrombophilic Defects

M. D. McColl; J. E. Ramsay; R. C. Tait; I. D. Walker; F. McCall; J. A. Conkie; M. J. Carty; I. A. Greer

doi:10.1055/s-0037-1615056

Thrombosis and Haemostasis, Inhaltsverzeichnis

Thromb Haemost 1998; 79(04): 741-742
DOI: 10.1055/s-0037-1615056

Rapid Communication

Schattauer GmbH

Superficial Vein Thrombosis: Incidence in Association with Pregnancy and Prevalence of Thrombophilic Defects

Authors

M. D. McColl

¹From the Dept. of Haematology, Royal Infirmary, Glasgow, UK.
J. E. Ramsay

²From the Glasgow Royal Maternity Hospital, Glasgow, UK
R. C. Tait

³From the Southern General NHS Trust, Glasgow, UK
I. D. Walker

¹From the Dept. of Haematology, Royal Infirmary, Glasgow, UK.
F. McCall

¹From the Dept. of Haematology, Royal Infirmary, Glasgow, UK.
J. A. Conkie

¹From the Dept. of Haematology, Royal Infirmary, Glasgow, UK.
M. J. Carty

³From the Southern General NHS Trust, Glasgow, UK
I. A. Greer

²From the Glasgow Royal Maternity Hospital, Glasgow, UK

Abstract

Summary

Superficial venous thrombotic (SVT) events are a feature of thrombophilic abnormalities, particularly those involving the protein C pathway. We have determined the incidence of SVT associated with pregnancy and the early postpartum period in a retrospective study involving 72 000 deliveries. Fourty-nine cases occurring in 47 individuals were recorded, with an overall incidence of 0.68/1000 deliveries (95% CI 0.48-0.88). None had a previous history of deep vein thrombosis or pulmonary embolism. Most events occurred in the early post-partum period (0.54/1000 deliveries). Twenty-four/fourty-seven were screened for established thrombophilic abnormalities, with only 1 abnormality detected (FV^Leiden heterozygote). Thrombophilia may play a minor role in the aetiology of SVT associated with pregnancy, although a larger study is required to confirm this.

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Referenzen

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