Thromb Haemost 2000; 83(06): 966-967
DOI: 10.1055/s-0037-1613953
Letters to the Editor
Schattauer GmbH

Massive Skin Necrosis Associated to the Prothrombin Gene G20210A Mutation

Vicente García-Patos
1   From the Department of Dermatology, Hospitals Vall d’Hebron
,
Juan Carlos Souto
2   Unitat d’Hemostàsia i Trombosi, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
,
Antoni Castells
1   From the Department of Dermatology, Hospitals Vall d’Hebron
,
Jordi Fontcuberta
2   Unitat d’Hemostàsia i Trombosi, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received 21. Oktober 1999

Accepted after revision 31. Januar 2000

Publikationsdatum:
14. Dezember 2017 (online)

 

 
  • References

  • 1 Bauer KA. Coumarin-induced skin necrosis. Arch Dermatol 1993; 129: 766-8.
  • 2 Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3’-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996; 88: 3698-703.
  • 3 Lane DA, Mannucci PM, Bauer KA. et al. Inherited thrombophilia: Part 1. Thromb Haemost 1996; 76: 651-62.
  • 4 Martinelli I, Sacchi E, Landi G, Taioli E, Duca F, Mannucci PM. High risk of cerebral-vein thrombosis in carriers of a prothrombin-gene mutation and in users of oral contraceptives. N Engl J Med 1998; 338: 1793-7.
  • 5 Yang Y, Algazy KM. Warfarin-induced skin necrosis in a patient with a mutation of the prothrombin gene. N Engl J Med 1999; 349: 735.
  • 6 Morell A, Botella R, Silvestre JF, Betlloch Y, Alfonso MR, Ruiz MD. Livedo reticularis and thrombotic purpura related to the use of diphenhydramine associated with pyrithyldione. Dermatology 1996; 193: 50-1.
  • 7 Jorens PG, Coucke V, Selala MI, Schepens PJ. Fatal intoxication due to the combined use of heroin and pyrithyldione. Hum Exp Toxicol 1992; 11: 296-7.
  • 8 Calvo MJAlcantara, Llamas R, Alberola C, Cruz TCruz, Cruz EMartos, Marfagon N, Herreros de Tejada A. Efectos relacionados con la asociación difenhidramina-piritildiona. Farm Clin 1990; 07: 214-8.