Genotype Distribution of the ⁴⁶C/T Polymorphism of Coagulation Factor XII in the Japanese Population: Absence of Its Association with Ischemic Cerebrovascular Disease

• References

• 1 Catto AJ, Grant PJ. Risk factors for cerebrovascular disease and the role of coagulation and fibrinolysis. Blood Coagul Fibrinol 1995; 06: 497-510.
• 2 Kohler HP, Carter AM, Stickland MH, Grant PJ. Levels of activated FXII in survivors of myocardial infarction - Association with circulating risk factors and extent of coronary artery disease. Thromb Haemost 1998; 79: 14-8.
• 3 Miller GJ, Esnouf MP, Burgess AI, Cooper JA, Mitchel JP. Risk of coronary heart disease and actvation of factor XII in middle-aged men. Arterioscler Thromb Vasc Biol 1997; 17: 2103-6.
• 4 Kanaji T, Okamura T, Osaki K, Kuroiwa M, Shimoda K, Hamasaki N, Niho Y. A common genetic polymorphism (46C to T substitution) in the 5’-untranslated region of the coagulation factor XII gene is associated with low translation efficiency and decrease in plasma factor XII level. Blood 1998; 91: 2010-4.
• 5 Kohler HP, Futers TS, Grant PJ. FXII (46C/T) polymorphism and in vivo generation of FXII activity. Thromb Haemost 1999; 81: 745-7.
• 6 Special Report From the National Institute of Neurological Disorders and Stroke. Classification of Cerebrovascular Diseases III. Stroke 1990; 21: 637-76.
• 7 Gordon EM, Donaldson VH, Saito H, Su E, Ratnoff OD. Reduced titer of Hageman factor (Factor XII) in Orientals. Ann Intern Med 1981; 95: 697-700.