A long-range PCR method for genotyping promoter variants in the interleukin-6 gene

J.W. Stephens; J. M. Palmen; S. J. Hurel; S. E. Humphries

doi:10.1055/s-0037-1613587

Thrombosis and Haemostasis, Inhaltsverzeichnis

Thromb Haemost 2003; 89(04): 765-767
DOI: 10.1055/s-0037-1613587

Letters to the Editor

Schattauer GmbH

A long-range PCR method for genotyping promoter variants in the interleukin-6 gene

Authors

J.W. Stephens
J. M. Palmen
S. J. Hurel
S. E. Humphries

Abstract

Volltext

Referenzen

References
1 Humphries SE, Luong LA, Ogg MS, Hawe E, Miller GJ. The interleukin-6 -174G/C promot¬er polymorphism is associated with risk of coronary heart disease and systolic blood pres¬sure in healthy men. Eur Heart J 2001; 22: 2243-52.
2 Jones KG, Brull DJ, Brown LC, Sian M, Greenhalgh RM, Humphries SE, Powell JT. Interleukin-6, (IL-6) and the prognosis of abdominal aortic aneurysms. Circulation 2001; 103: 2260-5.
3 Brull DJ, Montgomery HE, Sanders J, Dhamrait S, Luong L, Rumley A, Lowe GDO, Humphries SE. Interleukin-6 gene -174G>C and -572G>C promoter polymorphisms are strong predictors of plasma interleukin-6 lev¬els after coronary artery bypass surgery. Arterioscler Thromb Vasc Biol 2001; 21: 1458-63.
4 Georges JL, Loukaci V, Poirer O, Evans A, Luc G, Arveiler D, Ruidavets JB. et al. Interleukin-6 gene polymorphisms and susceptibility to myocardial infarction: the ECTIM study. J Mol Med 2001; 79: 300-5.
5 Ferrari SL, Ahn-Luong L, Garnero P, Parker R, Humphries SE, Greenspan SL. Two promoter polymorphisms regulating interleukin-6 gene expression are associated with circula¬ting levels of C-reactive protein and markers of bone resorption in postmenopausal women. J Clin Endocrinol Metab 2003; 88 (01) 255-9.
6 Fishman D, Faulds G, Jeffery R, Mohamed-Ali V, Yudkin JS, Humphries SE, Woo P. The effect of novel polymorphisms in the inter¬leukin-6 (IL-6) gene on IL-6 trancription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 1998; 102: 1369-13.
7 Terry CF, Loukaci V, Green FR. Cooperative influence of genetic polymorphisms on inter-leukin 6 transcriptional regulation. J Biol Chem 2000; 24: 18138-44.