Correlation of Activated Clotting Time (ACT) with rFVIIa Infusion and Clinical Efficacy in a Patient with Glanzmann Thrombasthenia and Platelet Alloantibodies

• References

• 1 George JN, Caen JP, Nurden AT. Glanzmann’s thrombasthenia: the spectrum of clinical disease. Blood 1990; 75: 1383-95.
• 2 Bierhng P, Fromont P, Elbez A, Duedari N, Kieffer N. Early immunization against platelet glycoprotein IIIa in a newborn Glanzmann type I patient. Vox Sanguinis 1998; 55: 109-13.
• 3 Ito K. et al. Antibody removal therapy used successfully at delivery of a pregnant patient with Glanzmann’s thrombasthenia and multiple anti-platelet antibodies. Vox Sanguinis 1991; 61: 40-6.
• 4 Poon MC, Demers C, Jobin F, Wu JW. Recombinant factor VIIa is effective for bleeding and surgery in patients with Glanzmann thrombasthenia. Blood 1999; 94: 3951-3.