CC BY-ND-NC 4.0 · Synthesis 2019; 51(05): 1073-1086
DOI: 10.1055/s-0037-1611660
short review
Copyright with the author

Pyrroles as Dienes in (4+3) Cycloadditions

Fan Hu
,
Jerome P. L. Ng
,
State Key Laboratory of Synthetic Chemistry, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. of China   Email: [email protected]
› Author Affiliations
Funding support from the State Key Laboratory of Synthetic Chemistry, and the University of Hong Kong are gratefully acknowledged.
Further Information

Publication History

Received: 24 December 2018

Accepted: 30 December 2018

Publication Date:
06 February 2019 (online)


Published as part of the 50 Years SYNTHESIS – Golden Anniversary Issue

Abstract

This short review summarizes the examples to date of successful (4+3) cycloadditions, including formal (4+3) cycloadditions, where pyrrole derivatives reacted as the diene component, to provide aza-bridged bicyclic and polycyclic adducts.

1 Introduction

2 Unsubstituted Pyrroles as Dienes in (4+3) Cycloadditions

3 C-Substituted Pyrroles as Dienes in (4+3) Cycloadditions

4 Intramolecular Pyrrole (4+3) Cycloadditions

5 Conclusions

 
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