Semin intervent Radiol 2017; 34(04): 409-414
DOI: 10.1055/s-0037-1608864
Clinical Corner
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Heparin-Induced Thrombocytopenia and Thrombosis: Preventing your Thrombolysis Practice from Taking a HITT

Eric Wannamaker1, Kimi Kondo1, D. Thor Johnson1
  • 1Department of Radiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado
Further Information

Publication History

Publication Date:
14 December 2017 (online)


Heparin-induced thrombocytopenia and thrombosis (HITT) is an under-recognized cause of deep venous thrombosis treatment failure and of complications during catheter-directed thrombolysis. After a review of HITT pathophysiology, diagnosis, and management, three different cases are presented in this article. Each case highlights subtleties and challenges of HITT diagnosis and management. An example of a practical approach to the diagnosis of HITT is presented.