Semin intervent Radiol 2017; 34(04): 322-327
DOI: 10.1055/s-0037-1608703
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Metastatic Osseous Pain Control: Radiation Therapy

Josephine Kang1, Silvia C. Formenti1
  • 1Department of Radiation Oncology, New York Presbyterian Hospital/Weill Cornell Medical Center, New York, New York
Further Information

Publication History

Publication Date:
14 December 2017 (online)


Metastatic disease to the bone is a common manifestation of advanced cancer, and can result in pain, pathologic fractures, hypercalcemia, and overall functional compromise. External beam radiation is a proven, highly efficacious, and noninvasive therapy that can provide symptomatic relief from painful osseous lesions. When deciding upon the best treatment regimen, it is important to consider patient factors such as overall life expectancy, performance status, disease burden, and site of osseous metastatic pain. Determination of best treatment ideally requires multidisciplinary input from radiologists, medical oncologists, surgeons, pain management, and palliative care specialists together with radiation oncologists.