Antibacterial Activity of Anthemis tricolor Boiss. from Cyprus

The genus Anthemis (Asteraceae) is widely distributed in Europe, the Mediterranean region and Western Asia, with approximately 195 species [1]. Anthemis species contain essential oil, flavonoids, polyphenolic acids, terpene and sesquiterpene lactones [1,2]. Many of them have been used for centuries as a folk medicine for the treatment of various diseases [3]. There are many studies on the biological activities of some species of the genus especially antibacterial, antifungal, antispasmodic, anti-inflammatory and cytotoxic activities [1,2].

In present work, chloroform and methanol extracts obtained by Soxhlet apparatus the aerial parts of Anthemis tricolor Boiss, an endemic species collected from Turkish Republic of Northern Cyprus, were investigated for their antibacterial activity against Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis and Candida albicans using microbroth dilution method. According to the results, the extracts of Anthemis tricolor Boiss. showed moderate to weak inhibitory effects. The minimum inhibitory concentration (MIC) values were also ranged from 78 µg/mL to 1250 µg/mL for all the tested microorganisms. The strongest inhibitory effect was detected in chloroform extract against Enterococcus faecalis with a MIC value of 78 mg/mL.

[1] Jassbi AZ, Firuzi O, Miri R, Salhei S, Zare S, Zare M, Masroorbabanari M, Chandran JN, Schneider B, Baldwin IT. Pharm Biol, 2016; 54: 2044 – 2049.

[2] Uzel A, Guvensen A, Çetin A. J Ethnopharmacol, 2004; 95: 151 – 154.

[3] Baytop T. Therapy with Medicinal Plants in Turkey, Past and Present, 2nd ed, Istanbul, Nobel Medical Publishing; 1999.