Planta Medica International Open 2017; 4(S 01): S1-S202
DOI: 10.1055/s-0037-1608316
Lecture Session – Veterinary Phytomedicine & Animal Health
Georg Thieme Verlag KG Stuttgart · New York

EVM as one stop solution for mastitis: validated through clinical and reverse pharmacology

B Nair
1   EVM Herbal Centre, VUTRC, Tamil Nadu Veterinary and Animal Sciences University, Thanjavur 613 403 Tamil Nadu, India, Thanjavur, India
2   Trans-Disciplinary University, FRLHT, Bangalore, India
,
N Punniamurthy
1   EVM Herbal Centre, VUTRC, Tamil Nadu Veterinary and Animal Sciences University, Thanjavur 613 403 Tamil Nadu, India, Thanjavur, India
,
K Mekala
1   EVM Herbal Centre, VUTRC, Tamil Nadu Veterinary and Animal Sciences University, Thanjavur 613 403 Tamil Nadu, India, Thanjavur, India
,
MNB Nair
2   Trans-Disciplinary University, FRLHT, Bangalore, India
,
N Ramakrishnan
1   EVM Herbal Centre, VUTRC, Tamil Nadu Veterinary and Animal Sciences University, Thanjavur 613 403 Tamil Nadu, India, Thanjavur, India
› Author Affiliations
Further Information

Publication History

Publication Date:
24 October 2017 (online)

 

Mastitis continues to be a major problem in dairy industry causing severe economic loss to the farmers. A wide variety of antimicrobials have been extensively used through parenteral as well as intramammary route to treat the infectious cause. Ethnoveterinary formulation for mastitis comprising Aloe vera, Curcuma longa and calcium hydroxide has been clinically evaluated and has been found to be successful as a stand-alone treatment mode against mastitis. The phytochemical screening of the formulation revealed the presence of alkaloids, saponins, steroids, carbohydrates, flavonoids, terpenoids, triterpenoids, sterols, emodin and diterpenes. TLC autobiography revealed the antioxidant activity of flavonoids, phenols and glycosides (ICAR Report 2016). Critical analysis of the published literatures provides ample evidence for the antimicrobial, anti-inflammatory and immunomodulating potential of the formulation. It can be concluded that after topical application of the formulation the pharmacologically active components penetrate into the skin and eliminate the infectious agents, effectively reduce the inflammation by suppressing the release of inflammatory mediators, provide analgesic effect, prevent fibrosis and further modulate the immune system of the host [1] resulting in recovery of udder swelling and infection as well as milk production.

[1] Kshirsagar, A. D, P. V. Panchal, U. N. Harle, R. K. Nanda and H.M. Shaikh, 2014. Int. J. Inflam, 12. http://dx.doi.org/10.1155/2014/690596