Planta Medica International Open 2017; 4(S 01): S1-S202
DOI: 10.1055/s-0037-1608299
Poster Session
Georg Thieme Verlag KG Stuttgart · New York

Quantitative determination of Allicin in commercially available garlic-containing feedingstuff of dogs & comparison with toxic doses

I Hahn
1   1Institute for Animal Nutrition and Functional Plant Compounds, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine Vienna, Veterinärplatz 1, Vienna, Austria
,
I Fuhrmann
1   1Institute for Animal Nutrition and Functional Plant Compounds, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine Vienna, Veterinärplatz 1, Vienna, Austria
,
K Zitterl-Eglseer
1   1Institute for Animal Nutrition and Functional Plant Compounds, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine Vienna, Veterinärplatz 1, Vienna, Austria
› Author Affiliations
Further Information

Publication History

Publication Date:
24 October 2017 (online)

 

The use of six different, commercially available garlic containing feed materials and supplement feed of dogs were evaluated and discussed concerning possible benefits (against gastrointestinal parasites and ticks) and harmful effects.

Quantitative analysis of Allicin content by means of HPLC (Tab. 1) showed quite good quality of three tested products (“Anibio” garlic powder, “PerNaturam” and “Lunderland” both garlic granules). Levels as high as in Ph. Eur. 8 required for garlic powder (Allii sativi bulbi pulvis: at least 0.45% Allicin in dried material for pharmaceutical use) were achieved – although these products are feedingstuff and not herbal remedies. Three other products contained a smaller amount of garlic and therefore also a lower level of Allicin.

Various data and recommendations from feed industry have been compared with recommended doses of veterinary practice (unfortunately scientific literature about dose rates is lacking). However, health hazards for dogs can be excluded in these dosages because toxic thresholds (5 g fresh garlic/kg body mass dog/day for seven days [1] – this is equal to 1.25 g dried garlic) are not reached in dogs.

Reported efficacy for prophylaxis and treatment of endoparasitosis and tick infestation with garlic powder in folk medicine is not scientifically proven in-vivo in dogs and could not be confirmed so far – further studies are required.

Tab. 1: Content of garlic (Allium sativum) and Allicin in different feedingstuff of dogs, including fresh garlic and garlic spice granulate (HPLC, triple determination).

Product

Content

Allium sativum

Mean value Allicin in %

Anibio Pulver

100%

0.55

PerNaturam Granulat

100%

0.52

Lunderland Granulat

100%

0.46

Grau Tabletten

95%

0.28

Canina Pulver

13%

0.06

Trixie Granulat

5%

determination influenced by adjuvants,

exact specification not possible

Garlic fresh

100%

0.52

Garlic spice granulate

100%

0.66