Planta Medica International Open 2017; 4(S 01): S1-S202
DOI: 10.1055/s-0037-1608095
Poster Session
Georg Thieme Verlag KG Stuttgart · New York

Phenolic Compounds and Antioxidant Activity of Scorzonera pygmaea Sibth.& Sm. Subaerial Parts

A Sarı
1   Istanbul University, Faculty of Pharmacy, Department of Pharmacognosy,? stanbul, Turkey
,
H Şahin
1   Istanbul University, Faculty of Pharmacy, Department of Pharmacognosy,? stanbul, Turkey
,
N Özsoy
2   Istanbul University, Faculty of Pharmacy, Department of Biochemistry,? stanbul, Turkey
› Author Affiliations
Further Information

Publication History

Publication Date:
24 October 2017 (online)

 

The genus Scorzonera is a member of the family Asteraceae, subfamily Liguliflorae, tribe Lactuceae and is represented by around 160 species in the world. There are 52 species in Turkey and 31 of them are endemic. Scorzonera species are used in traditional medicine as analgesic, antirheumatic, anthelmintic, diuretic, wound healer, in the treatment of infertilitiy, gout, pulmonary edema, diarrhea, gastric ulcer, malign gastric cancer and hypertension (1,2). Previously dihydroisocoumarins, benzyl phthalides, flavonoids, lignans, neolignans, bibenzyl derivatives, phenolic acid derivates, kavalactones, sesquiterpenes and triterpenes were reported from Scorzonera species (2,3). In this study, S. pygmaea, the endemic species of Turkey was investigated. Three dihydroisocoumarins (thunberginol C, scorzocreticoside I and II), two phenolic acid derivatives (chlorogenic acid, 3,5-di-O-caffeoylquinic acid) were isolated and identified from subaerial parts using chromatographic and spectral methods. These compounds are reported for the first time from S. pygmaea. Thunberginol C is new for the genus Scorzonera. Total phenolic content and antioxidant capacity of the petroleum ether, choloroform, ethyl acetate and n-butanol fractions of the ethanol extract of subaerial parts of S. pygmaea were investigated via 5 different methods (ferric reducing/antioxidant power assay, inhibition of lipid peroxidation, scavenging activity of DPPH, superoxide and ABTS radicals). Ethyl acetate fraction showed the highest phenolic content and antioxidant capacity. This is the first report on the antioxidant activity of S. pygmaea.

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