J Pediatr Neurol 2018; 16(01): 025-028
DOI: 10.1055/s-0037-1605581
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Non-Hodgkin's Lymphoma Presenting as an Isolated Vertebral Collapse

Vinay Agarwal
Department of Neurology, S.S. Hospital of Neurosciences, Agra, Uttar Pradesh, India
,
Namit Singhal
Department of Neurosurgery, S. S. Hospital of Neurosciences, Agra, Uttar Pradesh, India
,
Anu Chawla
Department of Pathology, Immunohistochemistry, SRL Ranbaxy, Gurugram, Haryana, India
› Author Affiliations
Further Information

Publication History

08 January 2017

10 July 2017

Publication Date:
14 August 2017 (eFirst)

Abstract

Non-Hodgkin's lymphoma (NHL) presenting as an isolated vertebral collapse is a very rare condition. We present a case of non-Hodgkin's lymphoma presenting as L3 vertebral body collapse on MRI. Isolated vertebral involvement was seen without evidence of any lesion elsewhere. Workup for systemic evidence of malignancy with contrast-enhanced CT of chest and abdomen did not reveal any other lesion. The patient was operated for L3 transpedicular decompression and L2–L4 pedicle screw rod fixation. Biopsy revealed diffuse large B cell lymphoma (DLBCL), NOS. Diagnosis was further confirmed by a postoperative PET scan, which showed multiple deposits in perinephric fat and retroperitoneal lymph nodes. Patient was treated with CHOP-based chemotherapy.