J Pediatr Neurol 2018; 16(01): 025-028
DOI: 10.1055/s-0037-1605581
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Non-Hodgkin's Lymphoma Presenting as an Isolated Vertebral Collapse

Vinay Agarwal
Department of Neurology, S.S. Hospital of Neurosciences, Agra, Uttar Pradesh, India
Namit Singhal
Department of Neurosurgery, S. S. Hospital of Neurosciences, Agra, Uttar Pradesh, India
Anu Chawla
Department of Pathology, Immunohistochemistry, SRL Ranbaxy, Gurugram, Haryana, India
› Author Affiliations
Further Information

Publication History

08 January 2017

10 July 2017

Publication Date:
14 August 2017 (eFirst)


Non-Hodgkin's lymphoma (NHL) presenting as an isolated vertebral collapse is a very rare condition. We present a case of non-Hodgkin's lymphoma presenting as L3 vertebral body collapse on MRI. Isolated vertebral involvement was seen without evidence of any lesion elsewhere. Workup for systemic evidence of malignancy with contrast-enhanced CT of chest and abdomen did not reveal any other lesion. The patient was operated for L3 transpedicular decompression and L2–L4 pedicle screw rod fixation. Biopsy revealed diffuse large B cell lymphoma (DLBCL), NOS. Diagnosis was further confirmed by a postoperative PET scan, which showed multiple deposits in perinephric fat and retroperitoneal lymph nodes. Patient was treated with CHOP-based chemotherapy.