CC BY-NC-ND 4.0 · Int Arch Otorhinolaryngol 2018; 22(03): 220-224
DOI: 10.1055/s-0037-1605367
Original Research
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

The Effect of Methylphenidate on the Hearing of Children with Attention Deficit Hyperactivity Disorder

Onur İsmi
1   Department of Otorhinolaryngology, Mersin Üniversitesi, Mersin, Turkey
Veli Yildirim
2   Department of Child and Adolescent Psychiatry Mersin Üniversitesi, Mersin, Turkey
Yusuf Vayisoglu
1   Department of Otorhinolaryngology, Mersin Üniversitesi, Mersin, Turkey
Anis Togrul
1   Department of Otorhinolaryngology, Mersin Üniversitesi, Mersin, Turkey
Fevziye Toros
2   Department of Child and Adolescent Psychiatry Mersin Üniversitesi, Mersin, Turkey
Murat Unal
1   Department of Otorhinolaryngology, Mersin Üniversitesi, Mersin, Turkey
› Author Affiliations
Further Information

Publication History

17 January 2017

28 June 2017

Publication Date:
07 August 2017 (online)


Introduction There has been a sudden idiopathic hearing loss case presented after methylphenidate treatment in a child with attention deficit hyperactivity disorder (ADHD).

Objective This study was performed to reveal the probable ototoxic side effects of methylphenidate use in patients with ADHD.

Methods Thirty pediatric patients with ADHD were included in the study. Pure tone audiometry, speech discrimination scores, waves I, III, V absolute latencies and waves I-III, I-V, III-V interpeak latencies at the 80 dB nHL intensity after click stimulus auditory brainstem response (ABR) results were compared before and 3 months after methylphenidate treatment.

Results There were no statistically significant difference between pretreatment and posttreatment pure tone and speech audiometry findings and ABR results (p > 0.05 for all parameters).

Conclusion Methylphenidate can be regarded as a safe drug regarding ototoxic side effects. Additional studies with a larger sample size and longer follow-up may be needed.

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