CC BY-NC-ND 4.0 · Int Arch Otorhinolaryngol 2018; 22(03): 231-238
DOI: 10.1055/s-0037-1604463
Original Research
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Anatomical Variations in Patients with Ménière Disease: A Tomography Study

Lucas Resende Lucinda
Department of Otolaryngology – Head and Neck Surgery, Universidade Federal do Paraná, Curitiba, PR, Brazil
,
Daniela Dranka Cristoff
Instituto Paranaense de Otorrinolaringologia, Curitiba, PR, Brazil
,
Luiz Otávio De Mattos Coelho
Department of Radiology, Universidade Federal do Paraná, Curitiba, PR, Brazil
,
Otávio Pereira Lima Zanini
Department of Otolaryngology – Head and Neck Surgery, Santa Casa de Curitiba, Curitiba, PR, Brazil
,
Rita De Cassia Cassou Guimarães
Department of Otolaryngology – Head and Neck Surgery, Universidade Federal do Paraná, Curitiba, PR, Brazil
› Author Affiliations
Further Information

Publication History

18 April 2017

09 June 2017

Publication Date:
28 August 2017 (eFirst)

Abstract

Introduction The etiology of Ménière disease (MD), a difficult-to-treat condition with great morbidity, remains controversial in the literature. The possible clinical and diagnostic impact of anatomical variations of the temporal bone among patients with MD has been recently studied.

Objective To identify anatomical variations of the temporal bone associated with the diagnosis of MD.

Methods Thirty-seven patients were included, although each ear was considered separately (n = 74). A case group (nA = 33) was composed of the affected ears of patients with definite MD and a control group (nB = 41) was used consisting of the ears of individuals who did not meet the criteria for MD and of the contralateral ears from patients with unilateral disease. Tomographic images from the individuals included in the study were submitted to a blinded and systematic evaluation regarding a broad variety of anatomical variations of the temporal bone. Obtained data were compared statistically between the groups and after stratifying the study sample. Significance level was set at 0.05.

Results Among the affected ears, it was observed an increased number of tomographic scans in which the vestibular aqueduct could not be identified (p = 0.01, Fisher exact test). No statistically significant differences were observed when comparing the affected and contralateral ears from patients with unilateral MD, between affected ears from patients with unilateral and bilateral disease or between contralateral ears of patients with unilateral affection and patients without the disease.

Conclusion Some anatomical variations might be more frequent in the affected ears of patients with MD, such as the lower rates of individualization of the vestibular aqueduct.

Note

This paper has been chosen to be presented in the IFOS-ENT World Congress, which was held in Paris, in June of 2017.