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J Neurol Surg A Cent Eur Neurosurg 2018; 79(01): 096-100
DOI: 10.1055/s-0037-1604326
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Primary Amelanotic CNS Melanoma: Case Report and Literature Review

Simon Mayer
1   Department of Neurosurgery, Bundeswehrkrankenhaus Ulm, Ulm, Baden-Württemberg, Germany
,
Uwe Max Mauer
1   Department of Neurosurgery, Bundeswehrkrankenhaus Ulm, Ulm, Baden-Württemberg, Germany
,
René Mathieu
1   Department of Neurosurgery, Bundeswehrkrankenhaus Ulm, Ulm, Baden-Württemberg, Germany
,
Carsten Hackenbroch
2   Department of Radiology, Bundeswehrkrankenhaus Ulm, Ulm, Baden-Württemberg, Germany
,
Janine Knupfer
3   Department of Dermatology, Bundeswehrkrankenhaus Ulm, Ulm, Baden-Württemberg, Germany
,
Chris Schulz
1   Department of Neurosurgery, Bundeswehrkrankenhaus Ulm, Ulm, Baden-Württemberg, Germany
› Author Affiliations
Further Information

Publication History

15 December 2016

26 April 2017

Publication Date:
27 July 2017 (online)

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Abstract

Primary malignant melanomas of the central nervous system (CNS) are rarely seen entities in the clinical routine. Primary amelanotic melanomas are even rarer. In our literature review, we found only six case reports of primary amelanotic CNS melanomas. Our case report describes the course of a 71-year-old man with a primary amelanotic CNS melanoma with secondary spread to the spine.

Keywords

primary - amelanotic - central nervous system - melanoma
 

  • References

  • 1 Balakrishnan R, Porag R, Asif DS, Satter AM, Taufiq M, Gaddam SS. Primary intracranial melanoma with early leptomeningeal spread: a case report and treatment options available. Case Rep Oncol Med 2015; 2015: 293802
    PubMedGoogle Scholar
  • 2 Ma J, Zhang Z, Li S, Chen X, Wang S. Intracranial amelanotic melanoma: a case report with literature review. World J Surg Oncol 2015; 13: 182
    CrossrefPubMedGoogle Scholar
  • 3 Suranagi VV, Maste P, Malur PR. Primary intracranial malignant melanoma: A rare case with review of literature. Asian J Neurosurg 2015; 10 (01) 39-41
    Article in Thieme ConnectPubMedGoogle Scholar
  • 4 Wagner Jr RF, Gerard G, Sciubba JJ. Amelanotic melanoma of the lung and brain with fenestrated intrinsic tumor capillaries. Surg Neurol 1981; 15 (05) 384-388
    CrossrefPubMedGoogle Scholar
  • 5 Schuknecht B, Müller J, Nadjmi M. Maligne Melanome der Meningen—MR- und CT-Diagnostik [in German]. RoFo Fortschr Geb Rontgenstr Nuklearmed 1990; 152 (01) 80-86
    Article in Thieme ConnectPubMedGoogle Scholar
  • 6 Li Y, Wang S, Zhao JZ. Clinical manifestations and treatment of melanoma of the central nervous system: analysis of 15 cases [in Chinese]. Zhonghua Yi Xue Za Zhi 2004; 84 (02) 134-137
    PubMedGoogle Scholar
  • 7 Jacob S, Pye E, Hbahbih M, Messios N, Rajabally YA. Rapidly progressive bilateral ophthalmoplegia and enlarging sellar mass caused by amelanotic melanoma. J Neuroophthalmol 2006; 26 (01) 49-50
    CrossrefPubMedGoogle Scholar
  • 8 Schulz C, Waldeck S. Primäre amelanotische meningeale Melanomatose [in German]. Fortschr Neurol Psychiatr 2012; 80 (07) 402-406
    Article in Thieme ConnectPubMedGoogle Scholar
  • 9 Said S, Alkhateeb H, Cooper CJ. , et al. Primary central nervous system amelanotic melanoma in a Hispanic male: case report. Pol J Radiol 2014; 79: 199-202
    CrossrefPubMedGoogle Scholar