Differential Diagnosis between Bartholin Cyst and Vulvar Leiomyoma: Case Report

Abstract

Genital leiomyomas are rare tumors that can often be misdiagnosed as Bartholin cyst. We report a case of a 32-year-old patient who had a cystic nodulation in the left labium majus that was suggestive of Bartholin cyst. A resection surgery was performed, and the definitive histopathology diagnosis was vulvar leiomyoma. The macroscopic features of cystic lesions difficult the differential diagnosis between leiomyoma and Bartholin cyst; therefore, a histopathologic examination is often recommended.

Resumo

Os leiomiomas genitais são tumores raros, e frequentemente são diagnosticados como cisto de Bartholin. Relatamos o caso de uma paciente de 32 anos em que ocorreu nodulação cística no grande lábio esquerdo sugestiva de cisto de Bartholin. Uma cirurgia de ressecção foi realizada, e o diagnóstico histopatológico definitivo foi leiomioma vulvar. As características macroscópicas das lesões císticas dificultam o diagnóstico diferencial entre o leiomioma e o cisto de Bartholin, de modo que o exame histopatológico é frequentemente recomendado.

Keywords

vulvar neoplasms - Bartholin gland - leiomyoma - histology - case report

Palavras-Chave

neoplasias vulvares - glândula de Bartholin - leiomioma - histologia - relato de caso

Contribution to Authorship

KAST was responsible for the conception and design of the study, the acquisition of data, and the draft of the article; TM and MT critically revised the article for important intellectual content; LMP critically revised the article for important intellectual content, and gave the final approval for the version that was submitted; CEF gave the final approval for the version that was submitted.

Note

This research received no specific grants from any public, private or non-profit funding agencies.

• References

• 1 Weston G, Healy DL. Uterine fibroids. In: Shaw RW, Luesley D, Monga A. , editors. Gynaecology. 4th ed. Edinburgh: Elsevier Science; 2011. . p. 473–85
• 2 Hillard P. Benign diseases of the female reproductive tract. In: Berek J, Adashi E, Hillard P. , editors. Novak's gynecology. 12th ed. Baltimore: Williams & Wilkins; 1996. . p. 331–97.
• 3 Kunhardt Urquiza E, de la Cruz SI, Fernández Martínez RL, Hernández Zúñiga VE. Myomatosis of rare localization. Ginecol Obstet Mex 1997; 65 (12) 541-544
• 4 Fasih N, Prasad Shanbhogue AK, Macdonald DB. , et al. Leiomyomas beyond the uterus: unusual locations, rare manifestations. Radiographics 2008; 28 (07) 1931-1948
• 5 Reyad MM, Gazvani MR, Khine MM. A rare case of primary leiomyoma of the vulva. J Obstet Gynaecol 2006; 26 (01) 73-74
• 6 Zhao T, Liu X, Lu Y. Myxoid epithelial leiomyoma of the vulva: a case report and literature review. Case Rep Obstet Gynecol 2015; 2015: 894830
• 7 Pandey D, Shetty J, Saxena A, Srilatha PS. Leiomyoma in vulva: a diagnostic dilemma. Case Rep Obstet Gynecol 2014; 2014: 386432
• 8 Nielsen GP, Rosenberg AE, Koerner FC, Young RH, Scully RE. Smooth-muscle tumors of the vulva. A clinicopathological study of 25 cases and review of the literature. Am J Surg Pathol 1996; 20 (07) 779-793
• 9 Zlatkov V, Doganov N, Macaveeva V. is A case of simultaneous development of leiomyomas of the labia majora and the uterine corpus. Rev Fr Gynecol Obstet 1989; 84 (04) 351-353
• 10 Youssef A, Neji K, M'barki M, Ben Amara F, Malek M, Reziga H. Leiomyoma of the vulva. Tunis Med 2013; 91 (01) 78-80
• 11 Francis SA, Wilcox FL, Sissons M. Bartholin's gland leiomyoma: a diagnostic and management dilemma. J Obstet Gynaecol Res 2012; 38 (06) 941-943
• 12 Aguilera Martínez V, Pérez Santana ME, Avila Contreras MdeL, Mendoza E. [Vulvar leiomyoma. Report of a case]. Ginecol Obstet Mex 2011; 79 (06) 382-385 Spanish
• 13 Zhou J, Ha BK, Schubeck D, Chung-Park M. Myxoid epithelioid leiomyoma of the vulva: a case report. Gynecol Oncol 2006; 103 (01) 342-345
• 14 Spies JB, Bradley LD, Guido R, Maxwell GL, Levine BA, Coyne K. Outcomes from leiomyoma therapies: comparison with normal controls. Obstet Gynecol 2010; 116 (03) 641-652