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Journal of Pediatric Epilepsy 2017; 06(03): 125-132
DOI: 10.1055/s-0037-1603774
Review Article
Georg Thieme Verlag KG Stuttgart · New York

Insular Epilepsy: Clinical, Electrophysiological Features, and Surgical Treatment

Ahmad Marashly
1   Division of Pediatric Neurology, Children's Hospital of Wisconsin/Medical College of Wisconsin, Milwaukee, Wisconsin, United States
,
Sean Lew
2   Division of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States
,
Christopher Inglese
1   Division of Pediatric Neurology, Children's Hospital of Wisconsin/Medical College of Wisconsin, Milwaukee, Wisconsin, United States
,
Wade Mueller
2   Division of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States
› Institutsangaben
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Publikationsverlauf

04. Februar 2017

12. Mai 2017

Publikationsdatum:
12. Juni 2017 (online)

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Abstract

The insula, also known as the fifth lobe of the brain, is a phylogenetically older part of the cortex that forms the floor of the Sylvian fissure. It is densely connected with multiple regions in the brain, reflecting its rich functionality. Epilepsy arising from the insula has been only relatively recently described and characterized in details. Besides having unique features, the insula is believed to be the origin of seizures resembling those of suspected temporal or frontal lobe epilepsy that do not respond to traditional surgical resections. In this review article, we describe the gross and functional anatomy of the insula, clinical and electrophysiological manifestations of insular epilepsy, and surgical evaluation and treatment approaches.

Keywords

epilepsy - insula - semiology - surgery

Note

All authors have contributed substantially to the conception, design, writing, and revising of this work.


 

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