CC-BY-NC-ND 4.0 · Int Arch Otorhinolaryngol 2018; 22(01): 094-102
DOI: 10.1055/s-0037-1602819
Systematic Review
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Clinical Features and Treatment of Fibrous Histiocytomas of the Tongue: A Systematic Review

Austin Nguyen
1  Division of Dermatology, Creighton University School of Medicine, Omaha, Nebraska, United States
,
Adam Vaudreuil
1  Division of Dermatology, Creighton University School of Medicine, Omaha, Nebraska, United States
,
Paul Haun
2  Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States
,
Gabriel Caponetti
2  Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States
,
Christopher Huerter
1  Division of Dermatology, Creighton University School of Medicine, Omaha, Nebraska, United States
› Author Affiliations
Funding Sources No funding obtained.
Further Information

Publication History

31 October 2016

09 March 2017

Publication Date:
02 May 2017 (eFirst)

Abstract

Introduction Benign fibrous histiocytomas are common lesions of the skin that rarely affect the tongue. Such cases are available in the literature exclusively as case reports. Similarly, malignant fibrous histiocytoma, now classified as undifferentiated pleomorphic sarcoma, is exceedingly rare in the tongue and not fully understood.

Objectives This study systematically reviews the available literature discussing the clinical and pathological features of malignant and benign fibrous histiocytomas.

Data Synthesis A total of 20 cases were included in this review. Patient-level data were extracted from cases to include clinical presentation, workup, treatment, and outcome.

Conclusion Benign fibrous histiocytomas are consistent in clinical and histopathologic presentation. Surgical treatment provides excellent outcome, with no recurrence in all excised cases. Malignant tumors have a more aggressive clinical and pathological presentation. Surgical treatment with possible adjuvant radiotherapy resulted in recurrence in 40% of cases (follow-up of 24 months), and death due to disease in 47% of patients (follow-up of 19 months).