CC-BY-NC-ND 4.0 · Int Arch Otorhinolaryngol 2018; 22(01): 055-059
DOI: 10.1055/s-0037-1602702
Original Research
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

Adenotonsillar Hypertrophy in Pre-School Children with Sickle Cell Disease and Diagnostic Accuracy of the Sleep Disturbance Scale for Children

Carlos Rodolfo Tavares de Góis
Department of Medicine, Universidade Federal de Sergipe (UFS), Aracaju, SE, Brazil
,
Jeferson Sampaio D'Ávila
Department of Medicine, Universidade Federal de Sergipe (UFS), Aracaju, SE, Brazil
,
Rosana Cipolotti
Department of Medicine, Universidade Federal de Sergipe (UFS), Aracaju, SE, Brazil
,
Amanda da Silva Lira
Department of Statistics and Actuarial Sciences, Universidade Federal de Sergipe (UFS), São Cristóvão, SE, Brazil
,
Ana Letícia Leite Silva
Department of Medicine, Universidade Federal de Sergipe (UFS), Aracaju, SE, Brazil
› Author Affiliations
Further Information

Publication History

12 November 2016

18 March 2017

Publication Date:
02 May 2017 (eFirst)

Abstract

Introduction Adenotonsillar hypertrophy is more common in children with sickle cell disease, and can lead to sleep-disordered breathing.

Objectives To determine the frequency of adenotonsillar hypertrophy in pre-school children with sickle cell disease and assess the diagnostic accuracy of the sleep-disordered breathing subscale in the Sleep Disturbance Scale for Children.

Method Observational study with a group of 48 children with sickle cell disease and a control group of 35 children without the disease. The children underwent oropharingoscopy and video nasal endoscopy. The parents and/or guardians answered the questions of the subscale.

Results Adenotonsillar hypertrophy was observed in 25% of the children in the study group, and in 20% of the children in the control group, with no statistical difference between the groups. The subscale score ranged from 3 to 11 in both groups. There was a statistical significance in the study group. The average was 4.79 (standard deviation [SD] ± 2.50), with 4.19 (SD ± 1.72) among the children without adenotonsillar hypertrophy, and 6.5 (SD ± 3.40) among the children with adenotonsillar hypertrophy. There was also a statistical significance in the control group. The average was 5.23 (SD ± 2.81), with 4.44 (SD ± 2.2) among the children without adenotonsillar hypertrophy, and 7.87 (SD ± 2.89) among the children with adenotonsillar hypertrophy.

Conclusion Adenotonsillar hypertrophy was not associated with sickle cell disease in pre-school children. The subscale of sleep-disordered breathing in the Sleep Disturbance Scale for Children was a useful tool for the diagnostic suspicion of adenotonsillar hypertrophy in children in this age group.