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CC BY-NC-ND 4.0 · Int Arch Otorhinolaryngol 2017; 21(04): 347-350
DOI: 10.1055/s-0037-1599096
Original Research
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

P300: Waves Identification with and without Subtraction of Traces

Ana Carla Leite Romero
1   Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, Ribeirão Preto School of Medicine, Universidade de São Paulo, Ribeirão Preto, SP, Brazil
2   Department of Phonoaudiology, School of Philosophy and Sciences, Universidade Estadual Paulista Julio de Mesquita Filho, Marilia Campus, Marilia, SP, Brazil
,
Ana Cláudia Mirândola Barbosa Reis
1   Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, Ribeirão Preto School of Medicine, Universidade de São Paulo, Ribeirão Preto, SP, Brazil
,
Anna Caroline Silva de Oliveira
2   Department of Phonoaudiology, School of Philosophy and Sciences, Universidade Estadual Paulista Julio de Mesquita Filho, Marilia Campus, Marilia, SP, Brazil
,
Humberto de Oliveira Simões
3   Department of Neuroscience and Behavioral Sceinces, Universidade de São Paulo, Ribeirão Preto School of Medicine, Universidade de São Paulo, Ribeirão Preto, SP, Brazil
,
Cinthia Amorim de Oliveira Junqueira
4   Department of Phonoaudiology, Universidade de Sao Paulo Campus de Ribeirao Preto, Ribeirao Preto, São Paulo, SP, Brazil
,
Ana Cláudia Figueiredo Frizzo
2   Department of Phonoaudiology, School of Philosophy and Sciences, Universidade Estadual Paulista Julio de Mesquita Filho, Marilia Campus, Marilia, SP, Brazil
› Author Affiliations
Further Information

Publication History

02 September 2016

21 December 2016

Publication Date:
28 February 2017 (online)

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Abstract

Introduction The P300 test requires well-defined and unique criteria, in addition to training for the examiners, for a uniform analysis of studies and to avoid variations and errors in the interpretation of measurement results.

Objectives The objective of this study is to verify whether there are differences in P300 with and without subtraction of traces of standard and nonstandard stimuli.

Method We conducted this study in collaboration with two research electrophysiology laboratories. From Laboratory 1, we selected 40 tests of subjects between 7–44 years, from Laboratory 2, we selected 83 tests of subjects between 18–44 years. We first performed the identification with the nonstandard stimuli; then, we subtracted the nonstandard stimuli from the standard stimuli. The examiners identified the waves, performing a descriptive and comparative analysis of traces with and without subtraction.

Results After a comparative analysis of the traces with and without subtraction, there was no significant difference when compared with analysis of traces in both laboratories, within the conditions, of right ears (p = 0.13 and 0.28 for differences between latency and amplitude measurements) and left ears (p = 0.15 and 0.09 for differences between latency and amplitude measurements) from Laboratory 1. As for Laboratory 2, when investigating both ears, results did not identify significant differences (p = 0.098 and 0.28 for differences between latency and amplitude measurements).

Conclusion There was no difference verified in traces with and without subtraction. We suggest the identification of this potential performed through nonstandard stimuli.

Keywords

electrophysiology - evoked potentials - auditory - event-related potentials - P300 - methods
 

  • References

  • 1 Duarte JL. Potencial evocado auditivo de longa latência-P300 em indivíduos normais: valor do registro simultâneo em Fz e Cz. Rev Bras Otorrinolaringol 2009; 75 (02) 231-236
    CrossrefGoogle Scholar
  • 2 Sousa LCA, Piza MRT, Alvarenga KF, Cóser PL. Eletrofisiologia da audição e emissões otoacústicas: princípios e aplicações clínicas. São Paulo: Tecmedd; 2008. a. Chap. 2. Conceitos básicos e fundamentos neurofisiológicos;7–8
    Google Scholar
  • 3 Hoshii LA. Potencial evocado auditivo de longa latência em um grupo de crianças deficientes auditivas usuárias de aparelho de amplificação sonora indivídual: estudo de caso [dissertation]. Campinas: PUC-SP; 2010: 145
    Google Scholar
  • 4 Junqueira CAO, Colafêmina JF. Investigation of inter- and intra-examiner stability to P300 auditory identification: analysis of errors. Rev Bras Otorrinolaringol 2002; 68 (04) 468-478
    CrossrefGoogle Scholar
  • 5 Schochat E. Respostas de Longa Latência. Em: Carvallo, RMM, organizadora. Fonoaudiologia: Informação para Formação - Procedimentos em Audiologia. Rio de Janeiro: Editora Guanabara Koogan; 2003: 71-7
    Google Scholar
  • 6 Matas CG, Hataiama NM, Gonçalves IC. Estabilidade dos potenciais evocados auditivos em indivíduos adultos com audição normal. Rev Soc Bras Fonoaudiol 2011; 16 (01) 37-41
    CrossrefGoogle Scholar
  • 7 Soares AJC, Sanches II SGG, Neves-Lobo IF, Carvallo RMM, Matas CG, Cárnio MS. Potenciais evocados auditivos de longa latência e processamento auditivo central em crianças com alterações de leitura e escrita: dados preliminares. Arq Int Otorrinolaringol 2011; 15 (04) 486-491
    Article in Thieme ConnectGoogle Scholar
  • 8 Rabelo CM, Neves-Lobo IF, Rocha-Muniz CN, Ubiali T, Schochat E. Cortical inhibition effect in musicians and non-musicians using P300 with and without contralateral stimulation. Rev Bras Otorrinolaringol (Engl Ed) 2015; 81 (01) 63-70
    Google Scholar
  • 9 Llloyd LL, Kaplan H. Audiometric interpretation: a manual of basic audiometry. University Park Press: Baltimore; 1978. ;94: 16-7
    Google Scholar
  • 10 Polich J. Bifurcated P300 peaks: P3a and P3b revisited?. J Clin Neurophysiol 1988; 5 (03) 287-294
    CrossrefPubMedGoogle Scholar
  • 11 Polich J. Normal variation of P300 from auditory stimuli. Electroencephalogr Clin Neurophysiol 1986; 65 (03) 236-240
    CrossrefPubMedGoogle Scholar
  • 12 Magliaro FCL, Scheuer CI, Assumpção Júnior FB, Matas CG. Study of auditory evoked potentials in autism. Pro Fono 2010; 22 (01) 31-36
    CrossrefPubMedGoogle Scholar
  • 13 Colin C. Avaliação comportamental e eletrofisiológica das funções auditivas no processo do envelhecimento [dissertation]. São Paulo: Faculdade de Medicina da Universidade de São Paulo; 2013: 129
    Google Scholar
  • 14 Näätänen R, Paavilainen P, Rinne T, Alho K. The mismatch negativity (MMN) in basic research of central auditory processing: a review. Clin Neurophysiol 2007; 118 (12) 2544-2590
    CrossrefGoogle Scholar