CC BY-NC-ND 4.0 · J Neurol Surg Rep 2017; 78(01): e1-e4
DOI: 10.1055/s-0036-1597692
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Primary Spinal Epidural Lymphoma As a Cause of Spontaneous Spinal Anterior Syndrome: A Case Report and Literature Review

M. E. Córdoba-Mosqueda
1   Department of Neurology and Neurosurgery, Hospital Central Sur de Alta Especialidad PEMEX, Mexico City, Mexico
,
J. R. Guerra-Mora
1   Department of Neurology and Neurosurgery, Hospital Central Sur de Alta Especialidad PEMEX, Mexico City, Mexico
,
M. C. Sánchez-Silva
2   Department of Radiology, Hospital Central Sur de Alta Especialidad PEMEX, Mexico City, Mexico
,
R. M. Vicuña-González
3   Department of Anatomical Pathology, Hospital Central Sur de Alta Especialidad PEMEX, Mexico City, Mexico
,
A. Ibarra-de la Torre
1   Department of Neurology and Neurosurgery, Hospital Central Sur de Alta Especialidad PEMEX, Mexico City, Mexico
› Author Affiliations
Further Information

Publication History

11 June 2016

07 November 2016

Publication Date:
23 January 2017 (online)

Abstract

Background Primary spinal epidural lymphoma (PSEL) is one of the rarest categories of tumors. Spinal cord compression is an uncommon primary manifestation and requires to be treated with surgery for the purpose of diagnosis and decompression.

Case Presentation A 45-year-old man presented with a new onset thoracic pain and progress to an anterior spinal syndrome with hypoesthesia and loss of thermalgesia. Magnetic resonance image showed a paravertebral mass that produces medullary compression at T3. The patient was taken up to surgery, where the pathology examination showed a diffuse large B-cell lymphoma.

Conclusions PSEL is a pathological entity, which must be considered on a middle-aged man who began with radicular compression, and the treatment of choice is decompression and biopsy. The specific management has not been established yet, but the literature suggests chemotherapy and radiotherapy; however, the outcome is unclear.

 
  • References

  • 1 Hirano K, Imagama S, Sato K. , et al. Primary spinal cord tumors: review of 678 surgically treated patients in Japan. A multicenter study. Eur Spine J 2012; 21 (10) 2019-2026
  • 2 Tsukada T, Ohno T, Tsuji K. , et al. Primary epidural non-Hodgkin's lymphoma in clinical stage IEA presenting with paraplegia and showing complete recovery after combination therapy. Intern Med 1992; 31 (04) 513-515
  • 3 Cho HJ, Lee JB, Hur JW, Jin SW, Cho TH, Park JY. A rare case of malignant lymphoma occurred at spinal epidural space: a case report. Korean J Spine 2015; 12 (03) 177-180
  • 4 Hirano K, Imagama S, Sato K. , et al. Primary spinal cord tumors: review of 678 surgically treated patients in Japan. A multicenter study. Eur Spine J 2012; 21 (10) 2019-2026
  • 5 Cugati G, Singh M, Pande A. , et al. Primary spinal epidural lymphomas. J Craniovertebr Junction Spine 2011; 2 (01) 3-11
  • 6 Çeçen DA, Tatarlı N, Turan Süslü H, Özdoğan S, Barışık NO. Primary dural spinal lymphoma presentation of a rare spinal tumor case. Case Rep Surg 2015; 2015: 639253
  • 7 Wada N, Kohara M, Ikeda J. , et al. Diffuse large B-cell lymphoma in the spinal epidural space: a study of the Osaka Lymphoma Study Group. Pathol Res Pract 2010; 206 (07) 439-444
  • 8 McDonald AC, Nicoll JAR, Rampling RP. Non-Hodgkin's lymphoma presenting with spinal cord compression; a clinicopathological review of 25 cases. Eur J Cancer 2000; 36 (02) 207-213
  • 9 Hong B, Hermann EJ, Reuter C, Brandis A, Krauss JK. Outcome of surgical decompression of spinal mass lesions in non-Hodgkin's lymphoma and plasmacytoma. Clin Neurol Neurosurg 2013; 115 (12) 2476-2481
  • 10 Epelbaum R, Haim N, Ben-Shahar M, Ben-Arie Y, Feinsod M, Cohen Y. Non-Hodgkin's lymphoma presenting with spinal epidural involvement. Cancer 1986; 58 (09) 2120-2124
  • 11 de Leval L, Hasserjian RP. Diffuse large B-cell lymphomas and Burkitt lymphoma. Hematol Oncol Clin North Am 2009; 23 (04) 791-827