Journal of Pediatric Neuroradiology 2016; 05(04): 248-252
DOI: 10.1055/s-0036-1597687
Original Article
Georg Thieme Verlag KG Stuttgart • New York

Influence of Oxygen Saturation and Age on Relaxation Time of Gray and White Matter and Diffusion Tensor Imaging Parameters in Children with Cardiac Malformations

Juan Leon-Wyss
1   Cardiovascular Center, CEDIMAT, Santo Domingo, Dominican Republic
Bernd Foerster
2   Department of Radiology, CEDIMAT, Santo Domingo, Dominican Republic
Cynthia Rosario
1   Cardiovascular Center, CEDIMAT, Santo Domingo, Dominican Republic
Janet Toribio
1   Cardiovascular Center, CEDIMAT, Santo Domingo, Dominican Republic
Herwin Speckter
2   Department of Radiology, CEDIMAT, Santo Domingo, Dominican Republic
Jairo Oviedo
2   Department of Radiology, CEDIMAT, Santo Domingo, Dominican Republic
Peter Stoeter
2   Department of Radiology, CEDIMAT, Santo Domingo, Dominican Republic
› Author Affiliations
Further Information

Publication History

13 November 2016

26 November 2016

Publication Date:
26 December 2016 (online)


The aim of this article is to investigate the influence of reduced arterial oxygenation on cerebral gray and white matter T2* time and parameters of diffusion tensor imaging (DTI) in children with cardiac malformations. In 23 patients examined by magnetic resonance imaging (3T), parameters were correlated to oxygen saturation and age (regression analysis). Reduced oxygen saturation correlated significantly to gray matter T2* time (p ≤ 0.01), whereas fractional anisotropy, mean diffusivity, and radial diffusivity correlated to age (p ≤ 0.005) but not to oxygenation. To conclude, gray matter T2* time might be used as a surrogate parameter to estimate oxygenation, and oxygenation does not influence the evaluation of DTI parameters.

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