Planta Med 2016; 82(S 01): S1-S381
DOI: 10.1055/s-0036-1596424
Abstracts
Georg Thieme Verlag KG Stuttgart · New York

Phytonutrients and bioactive compounds in the leaves of Solenostemon monostachyus

IS Afolabi
1  Covenant University, College of Science and Technology, School of Natural and Applied Sciences, Department of Biological Sciences, Biochemistry Unit, Canaan land, Km. 10, Idiroko road, P.M.B. 1023, Ota, Ogun State, Nigeria
,
AF Jolaoluwa
2  Liquid Bulk Limited, Aker Road, Rumuolumeni, Port Harcourt, Rivers State, Nigeria
,
VO Awogbindin
1  Covenant University, College of Science and Technology, School of Natural and Applied Sciences, Department of Biological Sciences, Biochemistry Unit, Canaan land, Km. 10, Idiroko road, P.M.B. 1023, Ota, Ogun State, Nigeria
,
PT Amosun
1  Covenant University, College of Science and Technology, School of Natural and Applied Sciences, Department of Biological Sciences, Biochemistry Unit, Canaan land, Km. 10, Idiroko road, P.M.B. 1023, Ota, Ogun State, Nigeria
› Author Affiliations
Further Information

Publication History

Publication Date:
14 December 2016 (online)

 

Plants can either be consumed [1, 2] or used for medicinal purposes. Solenostemon monostachyus is a very nutritious and health beneficial plant, and its leaves have been traditionally used for treating diabetes, malaria, sickle cell anemia, hypertension, among other disorders. The methanolic extract of S. monostachyus leaves was used to reverse from 26.85% sickled blood of sickle cell patients to 1.90% [3]. This effect can be attributed to its bioactive compounds. The quantification of vitamins A, C, D and E, and twenty secondary metabolites in the plant leaves methanolic extract was performed by HPLC-(UV detector): vitamin A (0.824 ± 0.486 ng/g dry weight), vitamin E (1.355 ± 1.549 ng/g dry weight), ascorbic acid (57.229 ± 18.543 µg/g dry weight), hesperidin (13.67 ± 1.62 mg/g), rosmarinic acid (10.58 ± 0.52 mg/g), myricetin (10.22 ± 0.50 mg/g), chicoric acid (9.81 ± 0.00 mg/g), chlorogenic acid (6.02 ± 0.04 mg/g), genistein (4.90 ± 0.26 mg/g), caffeic acid (3.65 ± 0.20 mg/g), quercetin (1.19 ± 0.00 mg/g), p-coumaric acid (1.16 ± 0.01 mg/g), cinnamic acid (0.72 ± 0.04 mg/g), kaempferol (0.72 ± 0.25 mg/g), daidzein (0.71 ± 0.02 mg/g), apigenin (0.35 ± 0.00 mg/g), lutein (0.26 ± 0.00 mg/g) and luteolin (0.17 ± 0.02 mg/g) were detected and quantified. Hesperidin, myricetin, quercetin and apigenin were the major bioactive compound detected in this plant. This is the first study to identify the bioactive compounds in S. monostachyus.

Acknowledgements: The authors acknowledge Professor Ogi Okwumabua, of the University of Wisonsin, Madison, USA for facilitating the procurement of the standards used for this study. We are also grateful to Miss Precious Amosun and Miss Victoria Awogbindin for their assistance in this work. The financial support of Pastor F. A. Jolaoluwa is also highly appreciated.

Keywords: Bioactive, Solenostemon monostachyus, health, HPLC, nutraceutical, vitamins.

References:

[2] Malan DF, Neuba DFR. Traditional practices and medicinal plants use during pregnancy by Anyi-Ndenye women (Eastern Côte d'Ivoire). Afr J Reprod Health 2011; 15: 85 – 93

[3] Olabanji SO, Omobuwajo OR, Ceccato D, Adebajo AC, Buoso MC, Moschini G. Accelerator-based analytical technique in the study of some anti-diabetic medicinal plants of Nigeria. Nuclear Instruments and Methods in Physics Research Section B-Beam Interactions with Materials and Atoms 2008; 266: 2387 – 2390

[4] Afolabi IS, Osikoya IO, Fajimi OD, Usoro PI, Ogunleye DO, Bisi-Adeniyi T, O. Adeyemi A, Adekeye BT. Solenostemon monostachyus, Ipomoea involucrata and Carica papaya seed oil versus Glutathione, or Vernonia amygdalina: Methanolic extracts of novel plants for the management of sickle cell anemia disease. BMC Complement Altern Med 2012; 12: 262