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Journal of Pediatric Neuroradiology 2016; 05(02): 070-081
DOI: 10.1055/s-0036-1592660
Review Article
Georg Thieme Verlag KG Stuttgart • New York

Supratentorial Brain Tumors in Children

Anastasia K. Zikou
1   Department of Radiology, Medical School University of Ioannina, Ioannina, Greece
,
Vassileios Xydis
1   Department of Radiology, Medical School University of Ioannina, Ioannina, Greece
,
George Alexiou
2   Department of Neurosurgery, Medical School University of Ioannina, Ioannina, Greece
,
Maria I. Argyropoulou
1   Department of Radiology, Medical School University of Ioannina, Ioannina, Greece
› Author Affiliations
Further Information

Publication History

12 July 2016

26 July 2016

Publication Date:
26 September 2016 (online)

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Abstract

Brain tumors in children are the second most common type of pediatric tumors after leukemia and the most common occurring solid tumor. Brain tumors diagnosed during the first year of life have different features than those presenting later in childhood and are usually supratentorial. Magnetic resonance imaging is the modality of choice for the diagnosis and characterization of these tumors. Herewith, we provide a review of the imaging characteristics on conventional and advanced neuroimaging techniques of the most common supratentorial intracranial tumors in children.

Keywords

children - brain tumor - supratentorial
 

  • References

  • 1 Borja MJ, Plaza MJ, Altman N, Saigal G. Conventional and advanced MRI features of pediatric intracranial tumors: supratentorial tumors. Am J Roentgenol 2013; 200 (5) W483-503
    CrossrefPubMedGoogle Scholar
  • 2 Panigrahy A, Krieger MD, Gonzalez-Gomez I , et al. Quantitative short echo time 1H-MR spectroscopy of untreated pediatric brain tumors: preoperative diagnosis and characterization. Am J Neuroradiol 2006; 27 (3) 560-572
    PubMedGoogle Scholar
  • 3 Poussaint TY. Magnetic resonance imaging of pediatric brain tumors: state of the art. Top Magn Reson Imaging 2001; 12 (6) 411-433
    CrossrefPubMedGoogle Scholar
  • 4 Lanphear J, Sarnaik S. Presenting symptoms of pediatric brain tumors diagnosed in the emergency department. Pediatr Emerg Care 2014; 30 (2) 77-80
    CrossrefPubMedGoogle Scholar
  • 5 Rossi A, Gandolfo C, Morana G, Tortori-Donati P. Tumors of the spine in children. Neuroimaging Clin N Am 2007; 17 (1) 17-35
    CrossrefPubMedGoogle Scholar
  • 6 Tortori-Donati P, Rossi A, Biancheri R , et al. Brain Tumors. In: Tortori-Donati P, ed, Pediatric Neuroradiology Brain Head and Neck Spine. Berlin: Springer Verlag; 2005: 329-429
    Google Scholar
  • 7 Cha S. Update on brain tumor imaging: from anatomy to physiology. AJNR Am J Neuroradiol 2006; 27 (3) 475-487
    PubMedGoogle Scholar
  • 8 Ibrahim AS, Gomaa M, Sakr H , et al. Role of diffusion tensor imaging in characterization and preoperative planning of brain neoplasms. The Egyptian Journal of Radiology and Nuclear Medicine 2013; 44 (2) 297-307
    CrossrefPubMedGoogle Scholar
  • 9 Okamoto K, Ito J, Ishikawa K, Sakai K, Tokiguchi S. Diffusion-weighted echo-planar MR imaging in differential diagnosis of brain tumors and tumor-like conditions. Eur Radiol 2000; 10 (8) 1342-1350
    CrossrefPubMedGoogle Scholar
  • 10 Cha S, Knopp EA, Johnson G, Wetzel SG, Litt AW, Zagzag D. Intracranial mass lesions: dynamic contrast-enhanced susceptibility-weighted echo-planar perfusion MR imaging. Radiology 2002; 223 (1) 11-29
    CrossrefPubMedGoogle Scholar
  • 11 Chavhan GB, Babyn PS, Thomas B, Shroff MM, Haacke EM. Principles, techniques, and applications of T2*-based MR imaging and its special applications. Radiographics 2009; 29 (5) 1433-1449
    CrossrefPubMedGoogle Scholar
  • 12 Hoefnagels FW, Lagerwaard FJ, Sanchez E , et al. Radiological progression of cerebral metastases after radiosurgery: assessment of perfusion MRI for differentiating between necrosis and recurrence. J Neurol 2009; 256 (6) 878-887
    CrossrefPubMedGoogle Scholar
  • 13 Astrakas LG, Argyropoulou MI. Key concepts in MR spectroscopy and practical approaches to gaining biochemical information in children. Pediatr Radiol 2016; 46 (7) 941-951
    CrossrefPubMedGoogle Scholar
  • 14 Al-Okaili RN, Krejza J, Wang S, Woo JH, Melhem ER. Advanced MR imaging techniques in the diagnosis of intraaxial brain tumors in adults. Radiographics 2006; 26 (Suppl. 01) S173-S189
    CrossrefPubMedGoogle Scholar
  • 15 Tzika AA, Zarifi MK, Goumnerova L , et al. Neuroimaging in pediatric brain tumors: Gd-DTPA-enhanced, hemodynamic, and diffusion MR imaging compared with MR spectroscopic imaging. Am J Neuroradiol 2002; 23 (2) 322-333
    PubMedGoogle Scholar
  • 16 Lee CC, Ward HA, Sharbrough FW , et al. Assessment of functional MR imaging in neurosurgical planning. Am J Neuroradiol 1999; 20 (8) 1511-1519
    PubMedGoogle Scholar
  • 17 Wengenroth M, Blatow M, Guenther J, Akbar M, Tronnier VM, Stippich C. Diagnostic benefits of presurgical fMRI in patients with brain tumours in the primary sensorimotor cortex. Eur Radiol 2011; 21 (7) 1517-1525
    CrossrefPubMedGoogle Scholar
  • 18 Louis DN, Ohgaki H, Wiestler OD , et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 2007; 114 (2) 97-109
    CrossrefPubMedGoogle Scholar
  • 19 Patibandla MR, Bhattacharjee S, Uppin MS, Purohit AK. Outcome of supratentorial intraaxial extra ventricular primary pediatric brain tumors: A prospective study. J Pediatr Neurosci 2014; 9 (3) 216-220
    CrossrefPubMedGoogle Scholar
  • 20 Rosenfeld A, Listernick R, Charrow J, Goldman S. Neurofibromatosis type 1 and high-grade tumors of the central nervous system. Childs Nerv Syst 2010; 26 (5) 663-667
    CrossrefPubMedGoogle Scholar
  • 21 Barkovich AJ, Raybaud C. Pediatric Neuroimaging. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2012
    Google Scholar
  • 22 Horger M, Vogel MN, Beschorner R , et al. T2 and DWI in pilocytic and pilomyxoid astrocytoma with pathologic correlation. Can J Neurol Sci 2012; 39 (4) 491-498
    CrossrefPubMedGoogle Scholar
  • 23 Harris LM, Davies NP, Macpherson L , et al. Magnetic resonance spectroscopy in the assessment of pilocytic astrocytomas. Eur J Cancer 2008; 44 (17) 2640-2647
    CrossrefPubMedGoogle Scholar
  • 24 Wu X, Bandopadhayay P, Ng J, Ashley D, Chow CW. The evolution of the histology in pleomorphic xanthoastrocytomas in children: a study of 15 cases. Pathology 2011; 43 (1) 9-16
    CrossrefPubMedGoogle Scholar
  • 25 Moore W, Mathis D, Gargan L , et al. Pleomorphic xanthoastrocytoma of childhood: MR imaging and diffusion MR imaging features. Am J Neuroradiol 2014; 35 (11) 2192-2196
    CrossrefPubMedGoogle Scholar
  • 26 Paldino MJ, Faerber EN, Poussaint TY. Imaging tumors of the pediatric central nervous system. Radiol Clin North Am 2011; 49 (4) 589-616
    CrossrefPubMedGoogle Scholar
  • 27 Crespo-Rodríguez AM, Smirniotopoulos JG, Rushing EJMR. MR and CT imaging of 24 pleomorphic xanthoastrocytomas (PXA) and a review of the literature. Neuroradiology 2007; 49 (4) 307-315
    CrossrefPubMedGoogle Scholar
  • 28 Nikitović M, Stanić D, Pekmezović T , et al. Pediatric glioblastoma: a single institution experience. Childs Nerv Syst 2016; 32 (1) 97-103
    CrossrefPubMedGoogle Scholar
  • 29 Koeller KK, Rushing EJ. From the archives of the AFIP: oligodendroglioma and its variants: radiologic-pathologic correlation. Radiographics 2005; 25 (6) 1669-1688
    CrossrefPubMedGoogle Scholar
  • 30 Tice H, Barnes PD, Goumnerova L, Scott RM, Tarbell NJ. Pediatric and adolescent oligodendrogliomas. Am J Neuroradiol 1993; 14 (6) 1293-1300
    PubMedGoogle Scholar
  • 31 Chang YW, Yoon HK, Shin HJ, Roh HG, Cho JM. MR imaging of glioblastoma in children: usefulness of diffusion/perfusion-weighted MRI and MR spectroscopy. Pediatr Radiol 2003; 33 (12) 836-842
    CrossrefPubMedGoogle Scholar
  • 32 Singhal N, Agarwal V. Pediatric gliomatosis cerebri mimicking tubercular encephalitis. J Pediatr Neurosci 2015; 10 (4) 379-381
    CrossrefPubMedGoogle Scholar
  • 33 Bendszus M, Warmuth-Metz M, Klein R , et al. MR spectroscopy in gliomatosis cerebri. Am J Neuroradiol 2000; 21 (2) 375-380
    PubMedGoogle Scholar
  • 34 Desclée P, Rommel D, Hernalsteen D, Godfraind C, de Coene B, Cosnard G. Gliomatosis cerebri, imaging findings of 12 cases. J Neuroradiol 2010; 37 (3) 148-158
    CrossrefPubMedGoogle Scholar
  • 35 Maton B, Resnick T, Jayakar P, Morrison G, Duchowny M. Epilepsy surgery in children with gliomatosis cerebri. Epilepsia 2007; 48: 1485-1490
    CrossrefPubMedGoogle Scholar
  • 36 Goh S, Butler W, Thiele EA. Subependymal giant cell tumors in tuberous sclerosis complex. Neurology 2004; 63 (8) 1457-1461
    CrossrefPubMedGoogle Scholar
  • 37 Telfeian AE, Judkins A, Younkin D, Pollock AN, Crino P. Subependymal giant cell astrocytoma with cranial and spinal metastases in a patient with tuberous sclerosis. Case report. J Neurosurg 2004; 100 (5, Suppl Pediatrics): 498-500
    CrossrefPubMedGoogle Scholar
  • 38 Grajkowska W, Kotulska K, Jurkiewicz E, Matyja E. Brain lesions in tuberous sclerosis complex. Review. Review Folia Neuropathol 2010; 48 (3) 139-149
    PubMedGoogle Scholar
  • 39 Holveck A, Grand S, Boini S , et al. Dynamic susceptibility contrast-enhanced MRI evaluation of cerebral intraventricular tumors: preliminary results. J Neuroradiol 2010; 37 (5) 269-275
    CrossrefPubMedGoogle Scholar
  • 40 Kalantari BN, Salamon N. Neuroimaging of tuberous sclerosis: spectrum of pathologic findings and frontiers in imaging. Am J Roentgenol 2008; 190 (5) W304-9
    CrossrefPubMedGoogle Scholar
  • 41 Yuh EL, Barkovich AJ, Gupta N. Imaging of ependymomas: MRI and CT. Childs Nerv Syst 2009; 25 (10) 1203-1213
    CrossrefPubMedGoogle Scholar
  • 42 Wagner MW, Poretti A, Huisman TA, Bosemani T. Conventional and advanced (DTI/SWI) neuroimaging findings in pediatric oligodendroglioma. Childs Nerv Syst 2015; 31 (6) 885-891
    CrossrefPubMedGoogle Scholar
  • 43 Danchaivijitr N, Waldman AD, Tozer DJ , et al. Low-grade gliomas: do changes in rCBV measurements at longitudinal perfusion-weighted MR imaging predict malignant transformation?. Radiology 2008; 247 (1) 170-178
    CrossrefPubMedGoogle Scholar
  • 44 Smits M. Imaging of oligodendroglioma. Br J Radiol 2016; 89 (1060) 20150857
    CrossrefPubMedGoogle Scholar
  • 45 Koeller KK, Sandberg GD ; Armed Forces Institute of Pathology. From the archives of the AFIP. Cerebral intraventricular neoplasms: radiologic-pathologic correlation. Radiographics 2002; 22 (6) 1473-1505
    CrossrefPubMedGoogle Scholar
  • 46 Horská A, Ulug AM, Melhem ER , et al. Proton magnetic resonance spectroscopy of choroid plexus tumors in children. J Magn Reson Imaging 2001; 14 (1) 78-82
    CrossrefPubMedGoogle Scholar
  • 47 Krieger MD, Panigrahy A, McComb JG , et al. Differentiation of choroid plexus tumors by advanced magnetic resonance spectroscopy. Neurosurg Focus 2005; 18 (6A): E4
    PubMedGoogle Scholar
  • 48 Koeller KK, Rushing EJ. From the archives of the AFIP: pilocytic astrocytoma: radiologic-pathologic correlation. Radiographics 2004; 24 (6) 1693-1708
    CrossrefPubMedGoogle Scholar
  • 49 Shin JH, Lee HK, Khang SK , et al. Neuronal tumors of the central nervous system: radiologic findings and pathologic correlation. Radiographics 2002; 22 (5) 1177-1189
    CrossrefPubMedGoogle Scholar
  • 50 Im SH, Chung CK, Cho BK , et al. Intracranial ganglioglioma: preoperative characteristics and oncologic outcome after surgery. J Neurooncol 2002; 59 (2) 173-183
    CrossrefPubMedGoogle Scholar
  • 51 Hummel TR, Miles L, Mangano FT, Jones BV, Geller JI. Clinical heterogeneity of desmoplastic infantile ganglioglioma: a case series and literature review. J Pediatr Hematol Oncol 2012; 34 (6) e232-e236
    CrossrefPubMedGoogle Scholar
  • 52 Jurkiewicz E, Grajkowska W, Nowak K, Kowalczyk P, Walecka A, Dembowska-Bagińska B. MR imaging, apparent diffusion coefficient and histopathological features of desmoplastic infantile tumors-own experience and review of the literature. Childs Nerv Syst 2015; 31 (2) 251-259
    CrossrefPubMedGoogle Scholar
  • 53 Fernandez C, Girard N, Paz Paredes A, Bouvier-Labit C, Lena G, Figarella-Branger D. The usefulness of MR imaging in the diagnosis of dysembryoplastic neuroepithelial tumor in children: a study of 14 cases. Am J Neuroradiol 2003; 24 (5) 829-834
    PubMedGoogle Scholar
  • 54 Kovanlikaya A, Panigrahy A, Krieger MD , et al. Untreated pediatric primitive neuroectodermal tumor in vivo: quantitation of taurine with MR spectroscopy. Radiology 2005; 236 (3) 1020-1025
    Google Scholar
  • 55 Law M, Kazmi K, Wetzel S , et al. Dynamic susceptibility contrast-enhanced perfusion and conventional MR imaging findings for adult patients with cerebral primitive neuroectodermal tumors. AJNR Am J Neuroradiol 2004; 25 (6) 997-1005
    PubMedGoogle Scholar
  • 56 Koral K, Zhang S, Gargan L , et al. Diffusion MRI improves the accuracy of preoperative diagnosis of common pediatric cerebellar tumors among reviewers with different experience levels. AJNR Am J Neuroradiol 2013; 34 (12) 2360-2365
    CrossrefPubMedGoogle Scholar
  • 57 de León-Bojorge B, Rueda-Franco F, Anaya-Jara M. Central nervous system atypical teratoid rhabdoid tumor: experience at the National Institute of Pediatrics, Mexico City. Childs Nerv Syst 2008; 24 (3) 307-312
    CrossrefPubMedGoogle Scholar
  • 58 Koral K, Gargan L, Bowers DC , et al. Imaging characteristics of atypical teratoid-rhabdoid tumor in children compared with medulloblastoma. Am J Roentgenol 2008; 190 (3) 809-814
    CrossrefPubMedGoogle Scholar
  • 59 Meyers SP, Khademian ZP, Biegel JA, Chuang SH, Korones DN, Zimmerman RA. Primary intracranial atypical teratoid/rhabdoid tumors of infancy and childhood: MRI features and patient outcomes. Am J Neuroradiol 2006; 27 (5) 962-971
    PubMedGoogle Scholar
  • 60 Rorke LB, Packer R, Biegel J. Central nervous system atypical teratoid/rhabdoid tumors of infancy and childhood. J Neurooncol 1995; 24 (1) 21-28
    CrossrefPubMedGoogle Scholar
  • 61 Parmar HA, Hawkins C, Ozelame R, Chuang S, Rutka J, Blaser S. Fluid-attenuated inversion recovery ring sign as a marker of dysembryoplastic neuroepithelial tumors. J Comput Assist Tomogr 2007; 31 (3) 348-353
    CrossrefPubMedGoogle Scholar
  • 62 Smirniotopoulos JG, Rushing EJ, Mena H. Pineal region masses: differential diagnosis. Radiographics 1992; 12 (3) 577-596
    CrossrefPubMedGoogle Scholar
  • 63 Gavrilovic S, Lavrnic S, Thurnher M , et al. Proton MR spectroscopy and diffusion-weighted imaging of intracranial germ cell tumors: implications for differentiation from other lesions. Eur J Radiol Extra 2011; 79: e59-e64
    CrossrefPubMedGoogle Scholar
  • 64 Smith AB, Rushing EJ, Smirniotopoulos JG. From the archives of the AFIP: lesions of the pineal region: radiologic-pathologic correlation. Radiographics 2010; 30 (7) 2001-2020
    CrossrefPubMedGoogle Scholar