Organophotoredox/Copper Hybrid Catalysis for Regioselective Allylic­ Aminodecarboxylation of β,γ-Unsaturated Carboxylic Acids

Published as part of the Special Topic Modern Radical Methods and their Strategic Applications in Synthesis

Abstract

A new cooperative organophotoredox/copper catalysis allowing for the conversion of β,γ-unsaturated carboxylic acids into allylic hydrazides via radical regioselective allylic decarboxylative amination is reported. The coexistence of the copper catalyst is essential for the high yield and regioselectivity.

Key words

photoredox catalysis - copper - decarboxylation - β,γ-unsaturated carboxylic acids - allylic hydrazides - dual catalysis

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