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Synfacts 2017; 13(11): 1135
DOI: 10.1055/s-0036-1591613
Synthesis of Heterocycles
© Georg Thieme Verlag Stuttgart · New York

Selective N-Methylation of Pyrimidone with Chloro(chloromethyl)dimethylsilane–KF

Authors

    Contributor(s):

  • Victor Snieckus

  • Paramita Mukherjee (Pfizer)

Further Information

Publication History

Publication Date:
19 October 2017 (online)

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Key words

N-methylation - regioselectivity - pyrimidones - chloro(chloro)methyldimethylsilane - potassium fluoride