Iodine Monoacetate for Efficient Oxyiodinations of Alkenes and Alkynes

Tobias Hokamp; Alena Therese Storm; Mekhman Yusubov; Thomas Wirth

doi:10.1055/s-0036-1589119

Synlett, Inhaltsverzeichnis

Synlett 2018; 29(04): 415-418
DOI: 10.1055/s-0036-1589119

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Iodine Monoacetate for Efficient Oxyiodinations of Alkenes and Alkynes

Tobias Hokamp

^aSchool of Chemistry, Cardiff University, Park Place, Cardiff, CF10 3AT, UK eMail: wirth@cf.ac.uk

,

Alena Therese Storm

^aSchool of Chemistry, Cardiff University, Park Place, Cardiff, CF10 3AT, UK eMail: wirth@cf.ac.uk

,

Mekhman Yusubov

^bTomsk Polytechnic University and Siberian State Medical University, 634050 Tomsk, Russia

,

Thomas Wirth*

^aSchool of Chemistry, Cardiff University, Park Place, Cardiff, CF10 3AT, UK eMail: wirth@cf.ac.uk

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Abstract

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Published as part of the Cluster Alkene Halofunctionalization

Abstract

A novel and inexpensive, environmentally friendly method for the preparation of iodine monoacetate is presented using iodine and Oxone in acetic acid/acetic anhydride. The reagent is used in a highly efficient approach for the regio- and diastereoselective iodoacetoxylation of alkenes and alkynes in a simple one-pot process.

Key words

alkenes - alkynes - iodine - iodine(I)acetate - oxyiodination

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Referenzen

References and Notes

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