Synlett 2017; 28(01): 89-92
DOI: 10.1055/s-0036-1588912
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© Georg Thieme Verlag Stuttgart · New York

Mineral-Induced Enantioenrichment of Tartaric Acid

Dragos Gherasea, Robert M. Hazenb, Ramanarayanan Krishnamurthya, Donna G. Blackmond*a
  • aDepartment of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA   Email: blackmond@scrippps.edu
  • bDepartment of Earth Science, George Mason University, Fairfax, VA 22040, USA
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Publication History

Received: 22 September 2016

Accepted after revision: 26 October 2016

Publication Date:
15 November 2016 (eFirst)

Abstract

Interaction of mixtures of d- and l-tartrates with dissolved gibbsite minerals produces homochiral and heterochiral dimers in a stochastic manner, providing a mechanism for enantioenrichment given a small initial imbalance. This work offers the first suggestion for a path towards the emergence of homochirality in prebiotic metabolism via the glyoxylate scenario.

Supporting Information