CC-BY-NC-ND 4.0 · IJNS 2018; 07(01): 054-057
DOI: 10.1055/s-0036-1585460
Case Report
Thieme Medical and Scientific Publishers Private Ltd.

Giant Malignant Peripheral Nerve Sheath Tumor of Scalp in Non-neurofibromatosis Person: A Rare Case Report

Amit Gupta
1  Department of Neurosurgery, King Georges Medical Collage, Lucknow, Uttar Pradesh, India
,
Rakesh Kumar
1  Department of Neurosurgery, King Georges Medical Collage, Lucknow, Uttar Pradesh, India
,
Bal Krishna Ojha
1  Department of Neurosurgery, King Georges Medical Collage, Lucknow, Uttar Pradesh, India
,
Anil Chandra
1  Department of Neurosurgery, King Georges Medical Collage, Lucknow, Uttar Pradesh, India
› Author Affiliations
Further Information

Publication History

Received: 13 February 2016

accepted after revision: 11 March 2016

Publication Date:
12 April 2017 (eFirst)

Abstract

Malignant peripheral nerve sheath tumors (MPNSTs) are rare neoplasms, usually arising from components of nerve sheath such as perineural fibroblasts or Schwann cells. Primary scalp MPNST is an exceptionally rare entity and only few cases have been reported till date. We encountered an unusual case of giant scalp MPNST in a 70-year-old man without any history suggestive of neurofibromatosis associated with intracranial extension with underlying bone destruction. The tumor was treated with complete surgical excision followed by adjuvant radiotherapy. Histopathological examination showed hyper- and hypocellular areas of spindle cells admixed with myxoid areas and immunohistochemistry revealed positivity to vimentin and S100 on the basis of which the diagnosis of MPNST was made.