Journal of Pediatric Epilepsy 2016; 05(03): 122-132
DOI: 10.1055/s-0036-1584671
Review Article
Georg Thieme Verlag KG Stuttgart · New York

Atypical Evolutions of Idiopathic Focal Epilepsies in Childhood

Natalio Fejerman
1   Department of Neurology, Pediatric Hospital “Prof. Dr Juan P Garrahan,” Buenos Aires, Argentina
,
Roberto H. Caraballo
1   Department of Neurology, Pediatric Hospital “Prof. Dr Juan P Garrahan,” Buenos Aires, Argentina
,
Santiago Flesler
1   Department of Neurology, Pediatric Hospital “Prof. Dr Juan P Garrahan,” Buenos Aires, Argentina
› Author Affiliations
Further Information

Publication History

24 March 2016

13 April 2016

Publication Date:
27 June 2016 (online)

Abstract

Clinical and electroencephalographic (EEG) features of the three well-defined idiopathic focal epilepsies in childhood (IFEC)—benign childhood epilepsy with centrotemporal spikes (BCECTS), Panayiotopoulos syndrome, and the Gastaut type of idiopathic occipital epilepsy of childhood (IOEC-G)—have been clearly described and reported. It is also known that a significant percentage of children with IFEC present what were named atypical features in seizures and EEG abnormalities. We are studying here the small number of patients with IFEC who not only present atypical features, but also evolve into the spectrum of epileptic encephalopathies related with continuous spike-and-wave during sleep (CSWSS) or electrical status epilepticus during sleep (ESES), which includes atypical benign focal epilepsy of childhood, status of BCECTS, Landau-Kleffner syndrome, and CSWSS or ESES syndrome. We also emphasize that some patients with these encephalopathic course of IFEC present a mix or a sequence in time of the four mentioned subsyndromes.