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J Pediatr Infect Dis 2015; 10(04): 116-120
DOI: 10.1055/s-0036-1584180
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Extensive Osteomyelitis and Septic Arthritis Caused by Bacteroides Fragilis in a Child with Sickle Cell Disease: A Case Report

May Al Barrak
1   Pediatric Infectious Diseases Section, Prince Sultan Military Medical City, Riyadh, Saudi Arabia
,
Laila Alawdah
2   Pediatric Infectious Diseases, Microbiology Laboratory, Children's Specialized Hospital, King Fahad Medical City, Riyadh, Saudi Arabia
,
Dayel Alshahrani
2   Pediatric Infectious Diseases, Microbiology Laboratory, Children's Specialized Hospital, King Fahad Medical City, Riyadh, Saudi Arabia
,
Tariq Al Fawaz
2   Pediatric Infectious Diseases, Microbiology Laboratory, Children's Specialized Hospital, King Fahad Medical City, Riyadh, Saudi Arabia
,
Abeer Almezyad
2   Pediatric Infectious Diseases, Microbiology Laboratory, Children's Specialized Hospital, King Fahad Medical City, Riyadh, Saudi Arabia
,
Mohamed Alshehri
2   Pediatric Infectious Diseases, Microbiology Laboratory, Children's Specialized Hospital, King Fahad Medical City, Riyadh, Saudi Arabia
› Author Affiliations
Further Information

Publication History

05 January 2016

04 April 2016

Publication Date:
26 May 2016 (online)

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Abstract

Patients with sickle cell disease (SCD) have a higher risk of developing osteoarticular (OA) infections, which are most commonly caused by Salmonella and Staphylococcus aureus. Here, we report an unusual case of severe anaerobic osteoarticular infection caused by Bacteroides fragilis in an 11-year-old girl with SCD. Her management was challenging because she required joint aspiration twice, two rounds of surgical debridement, and a prolonged course of combined antimicrobial therapy to achieve clinical and biochemical improvement. To achieve good clinical outcomes, an anaerobic cause of OA infections should be considered in patients with SCD if improvement does not occur using the usual empirical antibiotic regimens.

Keywords

anaerobic bacterium - Bacteroides fragilis - osteomyelitis - septic arthritis - sickle cell disease
 

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