Geburtshilfe Frauenheilkd 2016; 76 - P61
DOI: 10.1055/s-0036-1583834

Contribution of the First Trimester Ultrasound Screening in the Diagnosis of Aneuploidies

F Mraihi 1, A Gharsa 1, S Schlomann 1, W Abdallah Med 1, A Achour 1, D Chelly 1
  • 1Department of gynecology and obstetrics A, Tunis, Tunisia


First trimester ultrasound has an important place in the early diagnosis of many fetal malformations and chromosomal abnormalities.


Highlight the performance and the contribution of ultrasonography in diagnosis of fetal malformations.


Prospective study over a period of a year, it covers all customers between 11 and 14 weeks pregnant.


On 2550 scans made during this period there were 343 ultrasounds for first trimester or 13%. The average age was 32.7%.

Among 343 validated nuchal translucency, 18 NT were pathological allowing the detection two cases of Trisomy 18 and a case of trisomy 21.

Morphological mini examination has identified 5 cases of cystic hygroma and 3 lethal malformations (excencephaly, rachischisis with hydrocephalus, anencephaly with omphalocele).

For the five cases of cystic hygroma, the trophoblast biopsy had been performed and had confirmed 2 cases of Trisomy 18.


First Trimester ultrasound screening joined in importance the morphological ultrasound. It allows a good morphological approach of the embryo, the measurement of the nuchal and it brings an excellent sign of appeal for the detection of chromosomal abnormalities.