Int J Angiol 2017; 26(01): 060-063
DOI: 10.1055/s-0036-1583522
Case Report
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Thoracic Aortic Aneurysm from Chronic Antiestrogen Therapy

Rishi Tripathi
1  Aortic Institute at Yale-New Haven, Yale University School of Medicine, New Haven, Connecticut
,
Sandeep Sainathan
1  Aortic Institute at Yale-New Haven, Yale University School of Medicine, New Haven, Connecticut
,
Bulat A. Ziganshin
1  Aortic Institute at Yale-New Haven, Yale University School of Medicine, New Haven, Connecticut
2  Department of Surgical Diseases, Kazan State Medical University, Kazan, Russia
,
John A. Elefteriades
1  Aortic Institute at Yale-New Haven, Yale University School of Medicine, New Haven, Connecticut
› Author Affiliations
Further Information

Publication History

11 January 2016

24 March 2016

Publication Date:
05 May 2016 (online)

Abstract

Aortic aneurysms are a common but often undetected pathology prevalent in the population. They are often detected as incidental findings on imaging studies performed for unrelated pathologies. Estrogens have been shown to exert a protective influence on aortic tissue. Pharmacological agents blocking the actions of estrogens may thus be implicated in causing aortic pathologies. We present the case of an elderly woman with breast carcinoma treated for 18 years with antiestrogen therapy who subsequently developed acute thoracic aortic deterioration (enlargement and wall disruption).